نتایج جستجو برای: like receptor 9

تعداد نتایج: 1595539  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Da-Wei Yeh Yi-Ling Liu Yin-Chiu Lo Chiou-Hwa Yuh Guann-Yi Yu Jeng-Fan Lo Yunping Luo Rong Xiang Tsung-Hsien Chuang

CpG-oligodeoxynucleotides (CpG-ODNs) are potent immune stimuli currently under investigation as antimicrobial agents for different species. Toll-like receptor (TLR) 9 and TLR21 are the cellular receptors of CpG-ODN in mammals and chickens, respectively. The avian genomes lack TLR9, whereas mammalian genomes lack TLR21. Although fish contain both of these genes, the biological functions of fish ...

2016
Yunjia Ren Li Hua Xiuping Meng Yue Xiao Xu Hao Sheng Guo Peiyan Zhao Luowei Wang Boqi Dong Yongli Yu Liying Wang

IL-17 is a proinflammatory cytokine produced by various immune cells. Polymorphonuclear neutrophils (PMNs) are the first line of defense in bacterial infection and express surface Toll-like receptor 9 (sTLR9). To study the relationship of sTLR9 and IL-17 in PMNs during bacterial infection, we infected mice with E. coli intraperitoneally to establish a septic peritonitis model for studying the P...

2016
Jian Shang Xiaobing Wang Wei Wang Huaqin Pan Shi Liu Lixia Li Liping Chen Bing Xia

PURPOSE The -1237T/C polymorphism of the Toll-like receptor 9 (TLR9) gene has been implicated in the susceptibility of inflammatory bowel diseases (IBDs), but the results remain conflicting. We further investigated this association via meta-analysis. MATERIALS AND METHODS Multiple electronic databases were extensively searched until February, 2015. The strength of association was evaluated by...

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