PCB and organochlorine pesticide residues were determined in otter (Lutra lutra) spraints (faeces) from nine catchment regions in SW England over the period 1989-1991. Results of analyses of tissues from 22 otters are also presented. Dieldrin occurred in the majority of spraint samples and p,p-DDE and total PCBs in all. Lindane occurred mainly in samples collected in spring. Lindane was not fou...

The effect of oral administration of lindane (gamma-HCH) has been studied on the intestine in 10-day, 20-day and 100-day old rats. In 10 day-old suckling pups exposed to lindane, there was a significant decrease in the activities of sucrase (29%), lactase (20%) and that of alkaline phosphatase (24%) compared to control. Sialic acid content of the brush borders was significantly decreased (29%) ...

The effects of different types of pesticides on the in vivo striatal dopamine release were investigated by using in vivo brain microdialysis technique. MPTP, paraquat, maneb, dicofol, DDT, lindane and flutriafol (1 mM) were administered directly into the striatum, and levels of dopamine and its metabolites dihydroxyphenylacetic acid (DOPAC) and homovallinic acid (HVA) were measured using HPLC-E...

Lindane, the y-isomer of 1,2,3,4,5,6-hexachlorocyclohexane, is a widely used organochlorine pesticide. The application of lindane in soil, foliar, and seed treatment for a large variety of fruit and vegetable crops, its application on livestock, pets, and on agricultural premises, in pharmaceutical prepa itions, as well as in public health pest control, could lead to the exposure of humans to l...

Total of 7,495 children including 3,908 boys and 3,587 girls from a kindergarten and 15 primary schools were examined for head lice infestation (HLI). The overall prevalence of HLI in this study was found to be 5.8%. Head lice were much more commonly detected in girls than in boys with prevalence of 11.2% and 0.9%, respectively. Sixty-nine children with HLI were treated with 1% lindane shampoo ...

The effect of environmental pollutants on honeybee behaviour has focused mainly on currently used pesticides. However, honeybees are also exposed to persistent organic pollutants (POPs). The aim of this laboratory based study was to determine if exposure to sublethal field-relevant concentrations of POPs altered the spontaneous behaviour of foraging-age worker honeybees. Honeybees (Apis mellife...

To test the hypothesis that some persistent organic pollutants contribute to the increased prevalence of allergic disease, the effects of selected compounds on cytokine production by PBMC from control and allergic donors were evaluated. Cells were cultured for six days in the presence of a xenobiotic (PCB 153, hexachlorobenzene, pentachlorobenzene, pentachlorophenol, lindane, atrazine or DMSO v...

With this letter Pesticide Action Network North America (PANNA), Alaska Community Action on Toxics (ACAT) and the 32 undersigned supporting organizations respectfully submit comments on EPA's Risk Assessment for the insecticide lindane and other HCH isomers. PANNA is the North America regional center for PAN International, a coalition of hundreds of environmental and other citizen organizations...