To determine the effects of steel factor (SIF) on the number and distribution of phenotypically defined hematopoietic stem cells in vivo, mice were treated with continuous s.c. infusions of SIF for up to 7 days. The bone marrow demonstrated a transient 5-fold increase in the number of c-kit-positive lineage-negative/low cells with no change in cellularity. The radioprotective capacity of bone m...

Developmental commitment involves activation of lineage-specific genes, stabilization of a lineage-specific gene expression program, and permanent inhibition of inappropriate characteristics. To determine how these processes are coordinated in early T cell development, the expression of T and B lineage-specific genes was assessed in staged subsets of immature thymocytes. T lineage characteristi...

Since 2007, West Nile virus (WNV) has been reported in South African horses, causing severe neurological signs. All cases were of lineage 2, except for one case that clustered with lineage 1 viruses. In the present study, gross and microscopic lesions of six South African lineage 2-infected horses and the one lineage 1 case are described. Diagnoses were confirmed by real-time reverse-transcript...

The concept of celebrities has shaped societies throughout history. This work addresses the problem of celebrity identification from social media interactions. “Celebritiness” is a characteristic assigned to persons that are initially based on specific achievements or lineage. However, celebritiness often transcends achievements and gets attached to the person itself, causing them to capture po...

objective(s):from the ancient era, emergence of agriculture in the connecting region of mesopotamia and the iranian plateau at the foothills of the zagros mountains, made iranian gene pool as an important source of populating the region. it has differentiated the population spread and different language groups. in order to trace the maternal genetic affinity between iranians and other populatio...

This paper examines intergenerational relations in Taiwan with a major focus on how the relations between second and third generations may be affected by prior family experiences between first, second and third generations. As a typical patriarchal family system, lineage differences regarding the effects of three-generation households on intergenerational relations are explored. Panel data from...

The t(12;21) translocation resulting in TEL/AML1 gene fusion is present in approximately 25% of patients with precursor B-lineage pediatric acute lymphoblastic leukemia (ALL). Studies suggest an association with a good prognosis; however, relapse can occur. We studied the relation between t(12;21), determined by fluorescence in situ hybridization or polymerase chain reaction, and in vitro drug ...

A real-time qPCR assay was designed to detect African-derived subspecies of western honey bees (Apis mellifera L.). The probes targeted the same region mitochondrial cytochrome b gene used in previous restriction enzyme assays. Using samples from 16 A. representing four lineages, we evaluated efficacy this identify African- (or A-lineage) and non-A-lineage bees. successfully differentiated A-li...