The risks of exposure to low dose ionizing radiation (below 100 mSv) are estimated by extrapolating from data obtained after exposure to high dose radiation, using a linear no-threshold model (LNT model). However, the validity of using this dose-response model is controversial because evidence accumulated over the past decade has indicated that living organisms, including humans, respond differ...

The universality of the target theory of radiation-induced effects is challenged by observations on non-targeted effects such as bystander effects and genomic instability. Essential features of non-targeted effects are that they do not require direct nuclear exposure by radiation and they are particularly significant at low doses. This new evidence suggests a need for a new paradigm in radiatio...

There is strong evidence that ionizing radiation increases cancer risks at high doses (e.g., >1 Gy), and persuasive, if controversial, epidemiological evidence that cancer risks are increased at low doses ( 10 mGy). Discussed here are the issues related to extrapolating radiation risks from low radiation doses to very low doses (<1 mGy) — for which purpose we are forced to rely on radiobiologic...

There is strong evidence that ionizing radiation increases cancer risks at high doses (e.g., >or=1 Gy), and persuasive, if controversial, epidemiological evidence that cancer risks are increased at low doses ( approximately 10 mGy). Discussed here are the issues related to extrapolating radiation risks from low radiation doses to very low doses (<or=1 mGy) - for which purpose we are forced to r...