نتایج جستجو برای: linked dextran microspheres

تعداد نتایج: 256278  

Bizhan Malaekeh-Nikouei Mahmoud R. Jaafari Nigel M. Davies Sayyed A. Sajadi Tabassi,

        The purpose of this study was to prepare and characterize microspheres loaded by cyclosporine A(CyA)-cyclodextrin (CD) complex. To achieve this goal, PLGA microspheres loaded by CyA CD complex were prepared by multiple emulsificationsolvent evaporation methods.Morphology, size, encapsulation efficiency and drug release from these microspheres were evaluated. Microscopic evaluation of mi...

Journal: :Biomaterials 1994
H F Cremers R F Wolf E H Blaauw J M Schakenraad K H Lam P Nieuwenhuis R Verrijk G Kwon Y H Bae S W Kim

The in vitro degradation properties of glutaraldehyde cross-linked albumin and albumin-heparin conjugate microspheres (AMS and AHCMS respectively) were evaluated using light microscopy, turbidity measurements and heparin release determinations, showing that the microspheres are degraded by proteolytic enzymes such as trypsin, proteinase K and lysosomal enzymes. The degradation rate was inversel...

M. MOOSAVI-NASAB SH. NAZEMI Z. ALAHDAD

In the present study, the production of dextran from date extract and sucrose as carbon sources by the bacterium Leuconostoc mesenteroides NRRL B512 (f) was investigated. In comparison to blue dextran (Mw≈2000 Da), dextran molecular weight was reduced (Mw2000 KDa). Flow behavior indices of dextran solutions from date extracts were investigated and rheological parameters were evaluated at concen...

2016

Also described as low viscous or low viscosity dextran, dextran 40 is prepared by acid hydrolysis and differential fractionation of a crude macromolecular polysaccharide produced from the fermentation of sucrose by the bacterium, Leuconostoc mesenteroides (strain B-512). The crude material is composed of linked glucose units. In the fraction represented by dextran 40, 80% of the molecules have ...

1999
HIROSHI NAKASE KAZUICHI OKAZAKI YASUHIKO TABATA SUGURU UOSE MASAYA OHANA KAZUSHIGE UCHIDA YUMI MATSUSHIMA CHIHARU KAWANAMI CHIKASHI OSHIMA YOSHITO IKADA TSUTOMU CHIBA

Several studies have indicated the involvement of macrophages and dendritic cells in active inflammatory bowel disease (IBD). Manipulation of these cells is considered a very important therapeutic strategy for patients with IBD. We evaluated the effect of a new drug delivery system targeting microfold cells and macrophages with poly(DL-lactic acid) microspheres containing dexamethasone (Dx). Co...

2014
Zhichao Zhang Yiming Yuan Bing Gao Jing Peng Wanshou Cui Weidong Song Zhongcheng Xin Yinglu Guo

Transl Androl Urol, Vol 3, Suppl 1 September 2014 www.amepc.org/tau © Translational Andrology and Urology. All rights reserved. free or pedicle grafts, and venous grafting for the corpora cavernosa, injection of synthetic dermal filler. Currently, as the need for safer, effective and less-invasive procedures is increasing, enhancement procedures using injectable products are in high demand. Inj...

Journal: :Advanced Functional Materials 2021

One of the main challenges in modern tissue engineering is to design biocompatible scaffolds with finely tuned porous architecture and capacity load bioactive molecules that guide growth differentiation cells during reconstruction. This work proposes a strategy alginate (PAS) well-tuned by leaching sacrificial vaterite CaCO3 microspheres packed alginate. Pore size interconnectivity depend on sp...

Journal: :Acta biomaterialia 2012
Gheorghe Fundueanu Marieta Constantin Ionela Oanea Valeria Harabagiu Paolo Ascenzi Bogdan C Simionescu

Preparation of cross-linked pH/thermoresponsive microspheres from preformed polymers is still lacking in literature since copolymers possessing both temperature- and pH-sensitive units together with a cross-linkable moiety in appropriate ratios are required. Moreover, choosing of the appropriate drugs able to be loaded and then released in a pulsatile manner is randomly performed. Here, we repo...

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