نتایج جستجو برای: linked immuno
تعداد نتایج: 244389 فیلتر نتایج به سال:
HCV is a positive strand RNA virus, and is a member of the Family Flaviviridie. HCV show substantial nucleotide sequence variability distributed throughout the viral genome, particularly the HVR1 region that is suggested to be immunogenic in humans. HVR1 is the most heterogeneous region within the E2 genome and peptide corresponding to this region, can be detected by homologous sera. To study t...
Production of immuno and biologically active erythropoietin was documented to occur in the human hepatoblastoma cell line HepG-2. The expression of the erythropoietin gene was further verified by Northern blot analysis using a single stranded RNA probe. In vitro studies showed that erythropoietin production by these cells was not stimulated by hypoxia or cobalt chloride, but was related to the ...
Immunotherapy is a promising strategy for the treatment of human epidermal growth factor receptor 2 (HER2)-positive tumors. Previously, we constructed an immuno-carboxy terminal fragment of Bid (immuno-tBid) and reported its specific and effective destruction of HER2-positive tumor cells. In this study, in order to further reduce the immunogenicity of the previous immuno-proapoptotic protein, w...
Excessive immune responses directed against foreign pathogens, self-antigens, or commensal microflora can cause cancer establishment and progression if the execution of tight immuno-regulatory mechanisms fails. On the other hand, induction of potent tumor antigen-specific immune responses together with stimulation of the innate immune system is a pre-requisite for effective anti-tumor immunity,...
Two lineages of Salmonella enterica serovar Typhimurium (S. Typhimurium) of multi-locus sequence type ST313 have been linked with the emergence of invasive Salmonella disease across sub-Saharan Africa. The expansion of these lineages has a temporal association with the HIV pandemic and antibiotic usage. We analysed the whole genome sequence of 129 ST313 isolates representative of the two lineag...
In order to provide better therapy we strive to increase our knowledge of how the immune system behaves and communicates in common pediatric immunological diseases, such as type 1 diabetes, allergic and celiac diseases. However, when dealing with pediatric diseases, where study subjects are almost exclusively children, blood volumes available for immunological studies are limited and as such mu...
A Plasmodium falciparum malaria blood stage antigen was isolated from in vitro parasite culture supernatant. The chemical composition of the antigen was studied by high-performance thin-layer chromatography, thin-layer chromatography, gas-liquid chromatography, and other chemical methods. Such analysis indicated it to be a glycophospholipid (GPL) and to be composed of xylose, mannose, galactose...
Brassica napus L., winter oilseed rape (OSR), is a major crop worldwide, with wide range of uses and high profitability. Viruses, such as turnip yellows virus (TuYV), are becoming increasingly important, in certain years, they can cause significant infestations OSR. It difficult to detect the presence during visual field inspections, symptoms it causes be confused either those caused by abiotic...
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