Cubosomes are cubic lipid-based delivery systems that can be an option for compounds have low solubility in water belonging to BCS grades II and IV. The aim of this literature review is get distinctive characteristics cubosomes the entrapment efficiency. was made by lipid (phytantriol, GMO) added with stabilizer using top-down or bottom-up method. Characterization instrument such as cryo-TEM (m...

The cellular distribution of the small hydrophobic (SH) protein in respiratory syncytial virus (RSV)-infected cells was examined. Although the SH protein was distributed throughout the cytoplasm, it appeared to accumulate in the Golgi complex within membrane structures that were enriched in the raft lipid, GM1. The ability of the SH protein to interact with lipid-raft membranes was further conf...

The stratum corneum (SC) is the outermost layer of the epidermis. Stacked intercellular lipid membranes found in the SC play a crucial role in regulating water transport through the skin. Despite the importance of this role of the SC lipid membranes, only a few studies have presented quantitative methods to measure the permeability of water in SC lipid membranes. In this work, we present a new ...

Nanostructured Lipid Carriers (NLC) are nano-sized colloidal drug delivery system that contains a lipid mixture consisting of both solid and liquid lipids in their core. This Lipid-Based Nanosystem is introduced as biocompatible, non-toxic, safe nano-drug compared to polymeric or metallic nanoparticles. Due its safety, stability, high loading capacity other lipid-based nanocarriers, NLC gained ...

Corresponding Author: Bruno Mégarbane, MD, Ph.D; e-mail: [email protected] We read with interest the article reporting Glasgow coma score (GCS) improvement in poisonings six hours after presentation, when using lipid emulsion (LE)1. The authors should be congratulated for this randomized investigation. However, we wish to comment on their findings. If considered as “antidote” for non-l...