نتایج جستجو برای: listeriolysin
تعداد نتایج: 486 فیلتر نتایج به سال:
Received ; accepted – 2 – ABSTRACT We present the results of reanalysis of low redshift Mg II absorption line sample compiled by Steidel and Sargent. We constructed grids of photoionization models for various cloud parameters. The conditions on cloud parameters to produce N(Fe II)≥N(Mg II) are obtained using single cloud curve of growth. Properties of Mg II absorbers with W(Fe II)/W(Mg II)(defi...
Listeria monocytogenes is a gram-positive facultative intracellular pathogen, causing serious illness in immunocompromised individuals and pregnant women. Upon detection by macrophages, which are key players of the innate immune response against infection, L. monocytogenes induces specific host cell responses which need to be tightly controlled at transcriptional and post-transcriptional levels...
OBJECTIVE The inadequate efficiency of existing therapeutic anti-cancer regiments and the increase in the multidrug resistance of cancer cells underscore the need to investigate novel anticancer strategies. The induction of apoptosis in tumors by cytotoxic agents produced by pathogenic microorganisms is an example of such an approach. Nevertheless, even the most effective drug should be deliver...
The presentation of microbial protein antigens by Major Histocompatibility Complex (MHC) molecules is essential for the development of acquired immunity to infections. However, most biochemical studies of antigen processing and presentation deal with a few relatively inert non-microbial model antigens. The bacterial pore-forming toxin listeriolysin O (LLO) is paradoxical in that it is cytotoxic...
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