نتایج جستجو برای: lithium topiramate mania treatment
تعداد نتایج: 1443141 فیلتر نتایج به سال:
Lithium has been a gold standard in the treatment of bipolar disorder (BD) for several decades. Despite a general reduction in the use of lithium over the past several years, it is effective in the management of both manic and depressive episodes in BD and continues to be recommended as a first-line mood stabilizer. This review provides an overview of the pharmacology of lithium and highlights ...
background lithium is a drug for treatment of bipolar disorder by correcting mania and reducing depressive mood swings. objectives in this study, effects of lithium on volumetric parameters of cerebellum were investigated using stereological methods. materials and methods in this experimental study, 20 sexually mature wistar male rats were selected and divided in two groups randomly (n = 10). a...
The Canadian Network for Mood and Anxiety Treatments (CANMAT) published guidelines for the management of bipolar disorder in 2005, with a 2007 update. This second update, in conjunction with the International Society for Bipolar Disorders (ISBD), reviews new evidence and is designed to be used in conjunction with the previous publications. The recommendations for the management of acute mania r...
INTRODUCTION A significant number of mania patients fail to respond to current pharmacotherapy, thereby there is need for novel augmentation strategies. The results of some early studies showed the effectiveness of cholinomimetics in the treatment of mania. One open case series suggested the efficacy of donepezil in the treatment of bipolar disorder. Our aim was to explore whether an oral choli...
OBJECTIVE Animal data suggest that subtherapeutic doses, including micro doses, of lithium may influence mood, and lithium levels in drinking water have been found to correlate with the rate of suicide. It has never been investigated whether consumption of lithium may prevent the development of bipolar disorder (primary prophylaxis). In a nation-wide population-based study, we investigated whet...
It has been over 60 years since Australian psychiatrist John Cade first described lithium’s therapeutic role in manic illness. Cade’s seminal 1949 article described the impact of lithium salts in resolving “psychotic excitement” in 10 manic patients. Since this discovery, lithium has become a gold standard treatment for bipolar disorder, with evidence supporting its role in acute mania, depress...
Noradrenergic and GABA systems may be involved in mania, but there is little information about relationships between the function of these systems and response to specific antimanic treatments. We investigated relationships between indices of catecholamine or GABA system function, pretreatment mania severity and antimanic response to divalproex, lithium, or placebo. Plasma GABA and urinary excr...
The treatment of bipolar disorder is complex and should involve a multidimensional approach, including psychopharmacology, psychoeducation and psychotherapy. This discussion of the optimal treatment for mania follows the steps that are outlined in the Canadian Network for Mood and Anxiety Treatments guidelines (Bipolar Disord 2005;7[Suppl 3]:5-69). Mrs. S is a 43-year-old married mother of 2 pr...
Still after more than 50 years, lithium is a major treatment of bipolar disorder, even though it has not been promoted by the pharmaceutical industry over the last decades. In recent years the evidence base on lithium for bipolar disorder has substantially increased due to results from a number of trials. Therefore, a review of this evidence is timely. The efficacy of lithium as an acute treatm...
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