HYPOTHESIS Bowel resection followed by chemotherapy is a better management strategy than immediate chemotherapy in asymptomatic patients with colorectal cancer and unresectable liver-only metastases at presentation. DESIGN Retrospective study. SETTING University hospital. PATIENTS Sixty-five consecutive symptom-free colorectal cancer patients with unresectable synchronous metastases confi...

a long-standing debate among the vocabulary researchers is the depth of processing to learn vocabulary. this paper is a quantitative research which considers a revision in the “involvement load hypothesis” proposed by laufer and hulstijn in 2001. it investigates the role of proficiency and evaluation in this hypothesis in order to better reveal its potential contribution to vocabulary learning....

Hepatoprotective effect of gallic acid against type 2-induced diabetic liver injury in male rats through modulation fetuin-A and GLP-1 with involvement ERK1/2/NF-κB Wnt1/β-catenin signaling pathways

Erdheim-Chester disease (ECD) is a rare form of systemic histiocytosis, typically presenting with striking osseous involvement characterized by bilateral osteosclerosis and involvement of organs such as the lung, pituitary gland, heart, and brain. Liver involvement with ECD is extremely uncommon. We report a 56-year-old woman presenting with newly diagnosed cirrhosis and signs concerning for in...

Primary involvement of liver in tuberculosis is a rare entity. It is difficult to diagnose in absence of previous history of tuberculosis or concurrent pulmonary involvement. It is usually misdiagnosed as neoplastic liver lesion, which misdirects the treatment protocol and delays proper treatment. Here we are presenting a case of 36-year-old male patient with vague right upper quadrant abdomina...

Based on the principal clinical and pathological features, autoimmune diseases can be broadly divided into localized (involving only a single organ or tissue) and systemic (involving multiple organs). The liver is a lymphoid organ that not only participates in the immune response, but also a target of autoimmune reactions. Autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary ...

papillon-lefevre syndrome (pls) is a very rare genetic syndrome, and fewer than 500 cases have been reported in the world. patients exhibit typical cutaneous involvement with hyperkeratosis, especially on the soles and palms, and early shedding of primary teeth. internal organ involvements, such as liver abscesses, have been described in case reports. this  communication  represents  the  first...

Systemic lupus Erythematosus (SLE) is a chronic inflammatory disease that affects multiple organs and systems such as skin, joints, kidneys, cardiovascular and central nervous systems. Twenty five to fifty percent of the patients with the diagnosis of SLE develop abnormal liver test during the course of the disease, being the main causes: hepatotoxic drugs, viral hepatitis and fatty liver disea...

Hydatidosis is endemic in Iran. We studied hydatid cyst pattern in children, compared it with adults and present our experience. In 40 children, 76 cyst were found. There were multiple large lung cysts unilateral or bilateral in children. In the liver, the chief complaint was abdominal pain and in the lung it was chest pain and asthma-like symptoms. Lung cysts were operated first and liver cyst...

Metastasis from colorectal carcinoma occurs by either lymphatic or hematogenous spread. The most common sites of colorectal metastasis are the liver and lung. Involvement of the skin, muscles and bones are quite rare. The prognosis in such patients is usually poor. Herewith, we are reporting a case of colonic carcinoma who had cutaneous metastasis, muscular involvement and diffuse skeletal meta...