Early reperfusion of the ischemic myocardium has been shown to reduce mortality in acute myocardial infarction. Unfortunately, reperfusion, although necessary to relieve ischemia, may be followed by morphological, functional, and electrical changes that result in additional myocardial damage, known as reperfusion injury. In animal models, several pharmacologic agents and reperfusion strategies ...

Minekawa, Ryoko, Takashi Takeda, Masahiro Sakata, Masami Hayashi, Aki Isobe, Toshiya Yamamoto, Keiichi Tasaka, and Yuji Murata. Human breast milk suppresses the transcriptional regulation of IL-1 -induced NFB signaling in human intestinal cells. Am J Physiol Cell Physiol 287: C1404–C1411, 2004. First published June 30, 2004; doi:10.1152/ajpcell.00471.2003.—Neonatal necrotizing enterocolitis (NE...

at present, liver transplantation remains the only curative option for the patients with cirrhosis and end-stage liver diseases. the survival rate and recurrent diseases remain the major issues in the patient post-transplantation. unani medicine is one of the oldest traditional systems of medicine which has been treating chronic liver diseases and cirrhosis (talayyaful-kabid) for centuries. the...

background: including multivariate survival data can be pointed competing risks data. there are various methods to analyze such data such as semi-parametric methods of cause-specific hazard function, and cumulative incidence function. the aim of this study was to deploy competing risks model to analyze the determinants of patients with liver cirrhosis. materials and methods: during the one-year...

hepatitis b infection is the main cause of liver related mortality in many countries including iran. liver transplantation in cirrhosis due to hbv infection before 1990 was an absolute contraindication. recurrent infection was a significant event in post liver transplant setting and resulted in increased risk of graft failure and death except successful transplanted individuals. advances in ant...

background:methotrexate (mtx) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (ra) which can be associated with toxic effects on different organs. this study was designed to investigate the hepatotoxic effects in ra patients treated with mtx. methods: in this cross-sectional observational study, ra patients who received standard do...

HEMOPEXIN IS A MULTIFUNCTIONAL serum glycoprotein that plays important roles in iron homeostasis, antioxidant protection, anti-inflammatory effects, and signal transduction pathways (6, 8). The liver is the main source of the hemopexin synthesis (7), but expression in other tissues including the retina, peripheral nerves, and neurons of the central nervous system has also been reported. Hemopex...

recognition of typhoid hepatitis is important since it has to be differentiated from other common ailments in our country such as viral, malarial or amoebic hepatitis. early institution of specific therapy in cases of typhoid hepatitis carries a good prognosis. in our study, 107 patients with positive blood or bone marrow cultures for salmonella typhi, were evaluated for hepatomegaly and abnorm...

background: the radioprotective effect of grewia asiatica fruit (gae) which contains anthocyanin type cyanidin 3- glucoside, vitamin c, a, minerals, carotenes and dietary fibers etc was studied. materials and methods: for study swiss albino mice were divided into five groups-1. control (vehicle treated) 2. gae treated (700 mg / kg. b.wt / day for fifteen days), 3. irradiated (5 gy), 4. gae + ir...

conclusions any discrepancy between histopathologic changes in time-zero biopsies and pattern of early liver laboratory alterations may be considered as a warning for causes other than pri. objectives the aim of this study was to show the correlation between histopathologic changes of pri and the alterations in liver tests in the early post-transplantation period. materials and methods between ...