Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT.  In the first step, following the purification of semi-crude DT by the ion-exchan...

Concrete is a material whose performance is governed by the subtle interaction of its cohesive and frictional constituents. Since the theories of plasticity, damage mechanics, and fracture mechanics cannot, by themselves, capture both of these phenomena, a novel constitutive model is proposed which combines the theories of plasticity and damage mechanics in a multi-surface formulation. Synthesi...

UNLABELLED Viscoelastic deformation of the contact volume between adhering bacteria and substratum surfaces plays a role in their adhesion and detachment. Currently, there are no deformation models that account for the heterogeneous structure and composition of bacteria, consisting of a relatively soft outer layer and a more rigid, hard core enveloped by a cross-linked peptidoglycan layer. The ...

Abstract. The main idea of the report is that the yield surface can be presented as thick, "foamed surface" with dimensionality exceeding two. By other words, perhaps, the yield surface is fractal, i.e. it belongs to the geometric objects with fractional dimensionality. Apparently, fractal structure of the yield surface is determined by the fractal structure of natural materials. Besides, the “...

one of the difficulties in using absolute altitudes is the separation between the mean open sealevel and geoid. theoretically, geoid is the base level in absolute altitudes, but practically, the mean open sealevel is used as a base level for absolute altitudes. the difference between these two levels is called as the seasurface topography. in this research, it is dealt the mean sea level modeli...

one of the difficulties in using absolute altitudes is the separation between the mean open sealevel and geoid. theoretically, geoid is the base level in absolute altitudes, but practically, the mean open sealevel is used as a base level for absolute altitudes. the difference between these two levels is called as the seasurface topography. in this research, it is dealt the mean sea level modeli...

A COUPLED CREEP-PLASTICITY MODEL FOR RESIDUAL STRESS RELAXATION OF A SHOT-PEENED NICKEL-BASE SUPERALLOY Name: Dennis Justin Buchanan University of Dayton, 2007 Advisor: Dr. R. A. Brockman Shot peening has been employed in numerous industries for decades to impart beneficial compressive residual stresses on the surface of metal components. Compressive residual stresses retard initiation of surfa...

Today, researchers exploit hybrid craft more than they used to be. The main reason is that they need to high speed as well as extra portability. For instance, a famous hybrid craft is named Hysucat, was designed through the combination of catamaran and hydrofoil. Catamarans, a type of multihull boats, have always considered by designers because of their simultaneous supply of high speed and sta...

In this paper, progressive damage and global failure of composite laminates under quasi-static, monotonic loading are investigated using 3D continuum damage mechanics. For this purpose, a finite element program has been developed using an eight-node 2D layered element including layer-wise plate theory. Damage analysis of a single orthotropic layer under various uniform in-plane and transverse l...

Purpose: The aim of the present study was to use finite elemental analysis (FEA) to evaluate bone stress near an implant placed at the border between the mandible and fibular graft in mandibular reconstruction. Materials and Methods: A fibular model (FM) and transplantation model (TM) were constructed for FEA. In TM, mandible was on the mesial side and the fibular graft was on the distal side. ...