A 56-year-old woman presented 30 minutes after onset of a right arm paresis. The cardiovascular risk factors included high cholesterol levels and heavy smoking, leading to a posterior myocardial infarction 6 years earlier, with stenting of a subtotal right coronary artery (RCA) ostial stenosis (3×13 mm bare metal stent). A symptomatic 70% RCA ostial restenosis, 9 months after initial percutaneo...

A prospective study was undertaken in March 1980, at the Vascular Surgery Department of the Padua University, Medical School, to establish whether patch graft angioplasty is useful in preventing restenosis after carotid endarterectomy (CE). Seventy-four patients underwent 86 CE (bilateral in 12 cases) for atherosclerotic disease involving the carotid bifurcation. Thirty-eight (51.4%) patients p...

OBJECTIVE Pericardial patches are commonly used in vascular surgery to close arteriotomies. The mechanism of early healing after patch implantation is still not well defined. We used a rat aortic patch model to assess pericardial patch healing and examined Ephrin-B2, a marker of arterial identity, expression within the post-implantation patch. We also determined whether endothelial progenitor c...

The antithrombotic and anticoagulant effects of recombinant wild type (WT) and mutated human activated protein C (hAPC) were investigated using a rat model of arterial thrombosis. Recent in vitro studies using human plasma have shown enhanced anticoagulant effects of hAPC by mutagenesis of either loop 148 in the serine protease domain or of the Gla domain. The Gla-domain mutant QGNSEDY-hAPC (= ...

AANA Journal/June 2007/Vol. 75, No. 3 193 Carotid endarterectomy is a procedure used to treat severe atherosclerotic occlusive disease involving the internal carotid arteries, most often at the common carotid artery bifurcation. The operation is performed by opening the common carotid arteries and the proximal internal carotid arteries in the neck, removing plaques from the inside of the arteri...

INTRODUCTION Surgical endarterectomy is the preferred method for treating occlusive disease of the common femoral artery (CFA). However, endarterectomy is not always straightforward in cases with heavily calcified plaque. To overcome this limitation, a new method for decalcification, which utilizes a Cavitron ultrasonic surgical aspirator (CUSA) has been developed. REPORT The method involves ...

This case describes a 60-year-old gentleman who presented with a pulsating mass behind his knee. Before this, he had a fasciotomy for suspected compartment syndrome of leg following knee arthroscopy, but this failed to resolve his leg symptoms. He was hemodynamically stable on presentation. His left calf was swollen with a circumference of 3 cm greater than right. There was a large pulsating ma...