This paper explores the concept of micro-architectural loops and discusses their impact on processor pipelines. In particular, we establish the relationship between loose loops and pipeline length and configuration, and show their impact on performance. We then evaluate the load resolution loop in detail and propose the distributed register algorithm (DRA) as a way of reducing this loop. It dec...

Cutis laxa is a rare inherited or acquired disorder of elastic tissue characterized by inelastic and loose skin. Congenital cutis laxa may present with internal organ involvement, determining a worse prognosis. The authors present the case of a female patient with clinical manifestations suggestive of the hereditary form of the disease, with consanguineous parents (second-degree cousins) and a ...

Different wipe materials and wetting agents have been traditionally used to collect pesticide residues from indoor surfaces in human exposure assessments. Such methods were developed to estimate human pesticide exposure through skin contact. From an environmental point of view, wiping methods may be also applied to predict the runoff potential of pesticides on urban impervious surfaces. Since l...

Ownership Domains generalize ownership types. They support programming patterns like iterators that are not possible with ordinary ownership types. However, they are still too restrictive for cases in which an object X wants to access the public domains of an arbitrary number of other objects, which often happens in observer scenarios. To overcome this restriction, we developed so-called loose ...

MukBs cooperate to loop DNA W hen it comes to corralling DNA, MukB is the little condensin that could, say Yuanbo Cui, Aoya Petrushenko, and Valentin Rybenkov (University of Oklahoma, Norman, OK). Small in size but with a big effect, condensins are believed to stabilize large DNA loops, thereby giving order to an otherwise tangled mess of chromatin. To investigate the mechanics of the E. coli c...

When representing textual documents by feature vectors for the purposes of further processing (e.g. for categorization, clustering, or visualization), one possible representation is based on “loose phrases” (also known as “proximity features”). This is a generalization of n-grams: a loose phrase is considered to appear in a document if all the words from the phrase occur sufficiently close to e...

We introduce loose graph simulations (LGS), a new notion about labelled graphs which subsumes in an intuitive and natural way subgraph isomorphism (SGI), regular language pattern matching (RLPM) and graph simulation (GS). Being an unification of all these notions, LGS allows us to express directly also problems which are “mixed” instances of previous ones, and hence which would not fit easily i...

Abstract Background: Obesity is a chronic condition with high prevalence and multifaceted etiologies; it accompanied by an increased risk of morbidity mortality. Bariatric surgeries (weight loss surgeries) include variety procedures performed on people who have obesity. Skin redundancy common post-bariatric complication. Abdominoplasty or "tummy tuck" cosmetic surgery procedure used to make the...

regions (Figure 1): the hindfoot or rearfoot (talus and calcaneus); the midfoot (navicular bone, cuboid bone, and three cuneiform bones); and the forefoot (metatarsals and phalanges). Differences between a newborn foot and an adult foot are summarized in Table 1. Simultaneous observation of both feet can reveal many deformities. The skin should be examined for unusual creases or folds that can ...