conclusions a complete immunohistochemical study should be considered in cases of malignant salivary gland tumors. to reduce the recurrence rate of these tumors, the optimum therapies are radiotherapy and chemotherapy. introduction salivary gland tumors are rare head and neck lesions. the majority are benign, with only 20% of cases malignant. an epithelial-myoepithelial carcinoma is a rare low-...

Background: Endostatin and bevacizumab have been approved for the first-line treatment of advanced non-small-cell lung cancer (NSCLC) patients in China; however, clinical outcomes each drug combined with platinum-based doublet chemotherapy (PT-DC) not yet directly compared. This study sought to assess 2 drugs PT-DC adenocarcinoma.

Background: Apelin has recently been considered as an adipokine secreted from visceral fat. Apelin and itsreceptor exist in many tissues including lung and play significant roles in many physiological andpathological activities. However, serum level of apelin-12 is unknown in smokers and in various types of lungmalignancies. There...

This study aimed to evaluate the biological role of geranylgeranyl diphosphate synthase (GGPPS) in the progression of lung adenocarcinoma. GGPPS expression was detected in lung adenocarcinoma tissues by qRT-PCR, tissue microarray (TMA) and western blotting. The relationships between GGPPS expression and the clinicopathological characteristics and prognosis of lung adenocarcinoma patients were a...

BACKGROUND To understand cartilage oligomeric matrix protein (COMP) mechanism network from human normal adjacent tissues to lung adenocarcinoma. METHODS COMP complete different activated (all no positive correlation, Pearson CC < 0.25) and uncomplete (partly no positive correlation except COMP, Pearson CC < 0.25) network were identified in higher lung adenocarcinoma compared with lower human ...

Background: The transformation of epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma (LUAD) into small cell cancer (SCLC) accounts for 3–14% the resistance mechanism to EGFR tyrosine kinase inhibitors (TKIs). At present, there is no relevant research explore dynamic expression EGFR-mutant proteins and genomic evolution in transformed SCLC/neuroendocrine carcinoma (NEC).

Abnormalities in the Notch signaling system are considered to play a role in the tumorigenesis of bronchiogenic carcinoma. The present study aimed to investigate the expression of Notch3 in adult lung cancer patients and its role in the pathogenesis of primary bronchiogenic carcinoma. The expression of the Notch3 protein in lung squamous cell carcinoma, adenocarcinoma, small cell carcinoma and ...

© Touch MEdical MEdia 2013 Abstract lung cancer is designated as either non-small-cell lung cancer (NSclc) or small-cell lung cancer. There are three subtypes of NSclc: adenocarcinoma (48 %), squamous cell carcinoma (28 %), and large-cell carcinoma (24 %). Epidermal growth factor receptor (EGFR) mutations, anaplastic lymphoma kinase (ALK) rearrangements, and ROS1 rearrangements are co-associate...

Background: Lung cancer is the second most commonly diagnosed malignancy and leading cause of death in 2020. Preliminary studies from 2014 to 2019 at Dr. Soedarso Hospital Pontianak showed there was an increase lung cases. This study aimed determine clinical profile patients with HospitalMethods: epidemiological used medical records 2017 2019. It a cross-sectional study, 81 samples met criteria...

Medicinal plants have been investigated for possible anti-cancer effects. The aim of the present study was to examine the cytotoxic activity of several medicinal plants on different tumor cell lines. 11 selected plant species which have been used in folkloric prescriptions were collected from different sites of Hamedan district of Iran. The methanolic extracts of the plants were prepared and th...