Detection of bone metastases in patients with lung cancer has important clinical significance and therapeutic implications, since it causes relevant changes in the patients’ treatment. This study compared the efficacies of 18F-fludeoxyglucose positron emission tomography (18F-FDG PET)/CT, and 99mTc bone scintigraphy [planar and single photon emission CT (SPECT))for detection of bone metastases ...

UNLABELLED Indium-111-labeled macroaggregated albumin (MAA) would be suitable for combined pulmonary perfusion and ventilation scan using a 99mTc ventilation agent. METHODS MAA suspended in 0.1 M sodium acetate buffer, pH 5.8, was incubated with 111In-chloride for 30 min at room temperature. An in vitro study of the obtained 111In-MAA was performed for labeling efficiency and stability in hum...

UNLABELLED Lung scintigraphy is primarily used to diagnose pulmonary embolism. Ventilation imaging is often performed using (99m)Tc-DTPA or Technegas, an ultrafine dispersion of (99m)Tc-labeled carbon. Despite the common use of these radioaerosols, they have not been compared in an intraindividual study, and not with ventilation-perfusion (V/P) SPECT. The aim of the present head-to-head study w...

STUDY OBJECTIVES We sought to investigate the effect of lung volume reduction surgery (LVRS) on regional lung ventilation. DESIGN Retrospective analysis of routinely acquired data before and after LVRS. SETTING Large, urban, university medical center. PATIENTS Twenty-nine patients with severe emphysema. INTERVENTION Bilateral LVRS. MEASUREMENTS AND RESULTS (133)Xe washout curves durin...

Unilateral absence of a pulmonary artery (UAPA) is a rare pulmonary vascular anomaly that is usually associated with other cardiac anomalies. We report a 9-year-old female diagnosed with isolated unilateral absence of the left pulmonary artery and a right aortic arch but without other cardiac anomalies. The only symptoms the patient had were recurrent respiratory tract infections. The chest x-r...

BACKGROUND In patients being considered for lung-resection surgery, quantitative perfusion scintigraphy is used to predict postoperative lung function and guide the determination of lung-resection candidacy. Vibration-response imaging has been proposed as a noninvasive, radiation-free, and simpler method to predict postoperative lung function. We compared vibration-response imaging to quantita...

UNLABELLED Lung volume reduction (LVR) is an effective therapy for end-stage emphysema. Preliminary and postprocedure imaging is usually limited to CT for anatomic delineation of the location and severity of the most acutely affected lung zones. The purpose of this study was to investigate the potential of using a new quantitative gas trapping index (GTI) derived from a (133)Xe ventilation scan...

the features of hypertrophic pulmunary osteoarthropathy (hpoa) on radionuclide bone scintigraphy have been well described in case reports and small series of patients. the aim of this study was to investigate prospectively the prevalence and distribution of hpoa in a large series of patients with carcinoma of the lung. two hundred and eleven patients aged 31-89 years (average age 66 years) male...

BACKGROUND Pulmonary hypertension has been suggested to play an important role in development of high-altitude pulmonary edema (HAPE), and individual susceptibility has been suggested to be associated with enhanced pulmonary vascular response to hypoxia. We hypothesized that much greater pulmonary vasoconstriction would be induced by acute alveolar hypoxia in HAPE-susceptible (HAPE-s) subjects ...