We present a rare complication after open-heart surgery resulting in compression of the superior vena cava (SVC) with the concurrent findings of the hypertrophic obstructive cardiomyopathy physiology. A 59-year-old woman developed a low cardiac output syndrome, persistent hypotension, and increasing filling pressures after emergency replacement of the ascending aorta and resuspension of the aor...

METHODS We included 426 HCM patients (44 14 years; 78% men) undergoing exercise echocardiography, excluding hypertensive heart disease of elderly, ejection fraction <50% and invasive therapy (myectomy or alcohol ablation) during follow-up. Clinical, echocardiographic (LV thickness, LVOT gradient, and MR) and exercise variables (percent of age-sex predicted metabolic equivalents [METs] and heart...

The relation to the pressure gradient as assessed by echocardiography and the CMR-derived planimetry of the LVOT is not known, no values for the differentiation of obstruction exist. We studied 37 patients with hypertrophic cardiomyopathy and 14 healthy controls using standard sequences with 3D coverage of the left ventricular outflow tract. A cutoff value of 2.7 cm2 identified obstruction as d...

Hypertrophic cardiomyopathy (HCM) is a genetic disease involving abnormal myocardium thickening. HCM can lead to dynamic left ventricular outflow tract obstruction (LVOT) that cause significant heart failure symptoms. A novel approach alleviate this LVOT involves atrioventricular node (AVN) ablation and right (RV) apical pacing along with radiofrequency (RF) an open irrigated catheter the thick...

BACKGROUND Surgical myectomy has been the standard treatment for patients with drug-refractory obstructive hypertrophic cardiomyopathy. The clinical and echocardiographic predictors of long-term survival and freedom from cardiovascular morbidity after myectomy have been unclear. METHODS AND RESULTS We studied a consecutive cohort of 338 adult patients (age at operation 47+/-14 [range 18 to 77...

BACKGROUNDS Idiopathic ventricular arrhythmias (VAs) originating from the left ventricular outflow tract (LVOT) sometimes require catheter ablation from both the endocardial and epicardial sides for their elimination, suggesting the presence of intramural VA foci. This study investigated the prevalence and electrocardiographic and electrophysiological characteristics of these idiopathic intramu...

Abbreviations: AR aortic regurgitation, AS aortic stenosis, AVA aortic valve area, CSA cross sectional area, CWD continuous wave Doppler, D diameter, HOCM hypertrophic obstructive cardiomyopathy, LV left ventricle, LVOT left ventricular outflow tract, MR mitral regurgitation, MS mitral stenosis, MVA mitral valve area, DP pressure gradient, RV right ventricle, RVOT right ventricular outflow trac...

Accessory mitral valve tissue is an extremely rare congenital cardiac anomaly of embryologic development of the endocardial cushion. This anomaly is often associated with left ventricular outflow tract obstruction (LVOTO). A 26-year-old pregnant female was referred to our Department of Cardiology with exertional shortness of breath and tachycardia. Transthoracic and transesophageal echocardiogr...

A thirty-two-year-old woman was admitted with complaints of fever, palpitations, and syncopal episodes for the last 3 months. On examination she was found to have elevated jugular venous pressure and pallor. Cardiovascular examination revealed loud first and second heart sounds with mid diastolic murmurs in mitral and tricuspid areas. ECG showed incomplete right bundle-branch block pattern. Tra...

A47-year-old woman with hypertrophic obstructive cardiomyopathy presented with worsening exertional dyspnea, paroxysmal nocturnal dyspnea, and chest pain, despite maximal medical therapy. Echocardiography showed severe ventricular hypertrophy, left ventricular outflow tract (LVOT) narrowing, a 110 mm Hg LVOT gradient, and systolic anterior motion of the mitral valve. She was referred for nonsur...