experimental  autoimmune  encephalomyelitis (eae)  is  a  mouse  model  for  multiple sclerosis (ms), this autoimmune disease is mainly mediated by adaptive and innate immune responses that lead to an inflammatory demyelination and axonal damage. imatinib mesylate is a  selective protein  tyrosine kinase inhibitor  with immunomodulatory  properties  that abrogates multiple signal transduction p...

the ability to maintain and study human tissues in in-vivo environment has proved to be a valuable tool in breast cancer research for several decades. the most widely tissues have been xenografts established human breast cancer cell lines into athymic nude mice. the aim of this study was to provide a new accurate and affordable method for the establishment of breast cancer xenograftin nude mice...

background: b-cell non-hodgkin’s lymphoma (nhl) is a common malignancy of lymphoid tissues. different types of nhl show various behaviors, prognoses, and responses to treatment. evaluation of disease activity in nhl can be helpful in managing and even increasing the patient’s survey. methods and results: in total, 121 patients (76 males and 45 females), and their age range were 18-53 years, wer...

i n m a n u f a c t u r i n g a c t i v i t i e s, i s s u e s s u c h a s t h e i n t e n s i t y o f c o m p e t i t i o n, r i s i n g a n d c h a n g i n g c u s t o m e r e x p e c t a t i o n s, a n d e v e r-i n c r e a s i n g t e c h n o l o g i c a l d e v e l o p m e n t s, i n t e n s i f y m a n u f a c t u r e r c o m m i t m e n t t o e l i m i n a t e d e f e c t s i n i t s p r...

context traumatic brain injury (tbi) is a leading cause of death, disability, and resource consumption per year. there are two kinds of brain injury in tbi, primary and secondary injuries. primary injury refers to the initial physical forces applied to the brain at the moment of impact. secondary injury occurs over a period of hours or days following the initial trauma and results from the acti...

800x600 abstract background: nursing is arguably one of the most dangerous jobs. since nurses are the largest providers of health care services in the community, their quality of life should be desirable to provide the high - quality care to the patients . the aim of this study was to examine the quality of life and its related factors among nurses in kashan shahid-beheshti hospital during 2013...

objective(s): recently, bone-avid radiopharmaceuticals have been shown to have potential benefits for the treatment of widespread bone metastases. although 177lutriethylene tetramine hexa methylene phosphonic acid (abbreviated as 177lu- tthmp), as an agent for bone pain palliation, has been evaluated in previous studies, there are large discrepancies between the obtained results. in this study,...

1-carboxymethyl-3-methylimidazolium chloride {[cmmim]cl} is utilized as a highly efficient and reusable catalyst for the synthesis of bis(indolyl)methanes by the condensation reaction of indole with arylaldehydes under solvent-free conditions at room temperature. in summary, the presented method have several advantages including simplicity, low cost, generality, efficiency, clean reaction profi...