PURPOSE The role of the Ferric Uptake Regulator (FUR) in the acid resistance of Helicobacter pylori (H. pylori) has been thought to be independent of urease. However, we demonstrated in this study that Fur influences urease activity. MATERIALS AND METHODS A fur knockout mutant of H. pylori was constructed by replacing the Fur gene with a kanamycin resistant marker gene. The wild-type H. pylor...

Previous experiments examining the transcriptional profile of the anaerobe Desulfovibrio vulgaris demonstrated up-regulation of the Fur regulon in response to various environmental stressors. To test the involvement of Fur in the growth response and transcriptional regulation of D. vulgaris, a targeted mutagenesis procedure was used for deleting the fur gene. Growth of the resulting Deltafur mu...

The ferric uptake regulator Fur is a well-known iron-responsive repressor of gene transcription, which is used by many bacteria to respond to the low-iron environment that pathogens encounter during infection. In this study we used comparative transcriptome analysis to define the role of the Fur protein in the global control of gene transcription and iron regulation in Neisseria meningitidis. B...

Ammonia fluxes in relation to cutting and fertilization of an intensively managed grassland derived from an inter-comparison of gradient measurements C. Milford, M. R. Theobald, E. Nemitz, K. J. Hargreaves, L. Horvath, J. Raso, U. Dämmgen, A. Neftel, S. K.Jones, A. Hensen, B. Loubet, P. Cellier, and M. A. Sutton Centre for Ecology and Hydrology (Edinburgh Research Station), Bush Estate, Penicui...

IV. Recherches fur quelques 'preparations chemiques, applique es a Vufage de la medecine; Hies a la feance publique de la faculte de medecine de Paris le 5 Novembre 1778 ; par M. Majault, D.R. de la dite faculte ?, augmentees depuis de plufieurs cbferuations en refutation de ce qu'on a publie fur les proprietes de /'alkali volatil fiuory celles du favon et du foyer de foufre. i. e. Inquiries co...

We have overexpressed and purified the Helicobacter pylori Fur protein and analyzed its interaction with the intergenic regions of divergent genes involved in iron uptake (frpB and ceuE) and oxygen radical detoxification (katA and tsaA). DNase I footprint analysis showed that Fur binds specifically to a high-affinity site overlapping the P(frpB) promoter and to low-affinity sites located upstre...

In the ancient anaerobic environment, ferrous iron (Fe(2+)) was one of the first metal cofactors. Oxygenation of the ancient world challenged bacteria to acquire the insoluble ferric iron (Fe(3+)) and later to defend against reactive oxygen species (ROS) generated by the Fenton chemistry. To acquire Fe(3+), bacteria produce low-molecular weight compounds, known as siderophores, which have extre...

The influence of epoxy active diluents, 1,4-butanediol diglycidyl ether (BD) and furfuryl glycidyl (FUR), in the mixtures with benzoxazine monomer based on bisphenol A, formaldehyde m-toluidine (BA-mt), properties a matrix was disclosed this work. Resins were modified to achieve good tackiness at room temperature reduced viscosity. mono- difunctional modifiers process curing studied by way diff...

es wird gezeigt, dass bei der standiger zunahme der production von roheisen ,die fast ausschliesslich in hochofen erfolgt, der gestelldurchmesser und die ofeneinheit zunimmt demgegenuber der spezifische brennstoffverbrauch abnimmt. weiterhin wird die entwicklungsrichtung der stahlerzeungsverfanren wegen der wirtschaftlichen und technischen hinsicht untersucht und festgestellt, dass nuter versch...