نتایج جستجو برای: macular degeneration

تعداد نتایج: 73965  

Journal: :The New England journal of medicine 2007
John R W Yates Tiina Sepp Baljinder K Matharu Jane C Khan Deborah A Thurlby Humma Shahid David G Clayton Caroline Hayward Joanne Morgan Alan F Wright Ana Maria Armbrecht Baljean Dhillon Ian J Deary Elizabeth Redmond Alan C Bird Anthony T Moore

BACKGROUND Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors. Complement activation is implicated in the pathogenesis. METHODS We tested for an association between age-related macular degeneration and 13 single-nucleotide polymorphisms (SNPs) spanning the complement genes ...

Journal: :Archives of ophthalmology 1998
T Ishibashi T Murata M Hangai R Nagai S Horiuchi P F Lopez D R Hinton S J Ryan

OBJECTIVE To investigate the localization of N epsilon-(carboxymethyl)lysine (CML), a component and major immunologic epitope of advanced glycation end products, in aged eyes and choroidal neovascular membranes (CNVMs) surgically excised from eyes with age-related macular degeneration. METHODS Immunohistochemistry for CML was performed using 8 snap-frozen, surgically excised CNVMs. Twelve eye...

Journal: :Survey of ophthalmology 2007
David Covert Gilles Berdeaux Jan Mitchell Clare Bradley Rod Barnes

In this article, we review measures of patient-reported outcomes that can show whether a treatment for age-related macular degeneration also provides patient-perceived benefits. In addition, we look at health economic measurements currently being used to develop cost-effectiveness models for age-related macular degeneration.

Journal: :CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2004
Erica Weir

Journal: :Brain : a journal of neurology 2012
Mathias Abegg Martin Zinkernagel Sebastian Wolf

Sir, We read with great interest the article by Gelfand et al. (2012) in the June issue of Brain. The authors described in detail vacuolar macular changes in the inner nuclear layer of patients with multiple sclerosis. This ‘microcystic macular oedema’ was associated with decreased visual acuity and a higher disability score. We found similar microcysts in the macular inner nuclear layer of a 1...

2014
Vijaya Juturu

MZ: Meso-Zeaxanthin; L: Lutein; RZ: RR-Zeaxanthin; AMD: Age-related Macular Degeneration; MD: Macular Degeneration; NAFL: Non-Alcoholic Fatty Liver; NASH: Nonalcoholic Steatohepatitis; DPPH: Diphenyl-2-Picrylhydrazyl; ABTS: 2, 2’-Azino-Bis (3-Ethylbenzothiazoline-6-Sulfonic acid); GST: Glutathione-S-Transferase; UDPGT: Uridine Diphosphate Glucuronyl Transferase; SGOT: Serum glutamic oxaloacetic...

Journal: :PLoS ONE 2008
Hendrik P. N. Scholl Peter Charbel Issa Maja Walier Stefanie Janzer Beatrix Pollok-Kopp Florian Börncke Lars G. Fritsche Ngaihang V. Chong Rolf Fimmers Thomas Wienker Frank G. Holz Bernhard H. F. Weber Martin Oppermann

Journal: :Ophthalmology 2014
Daniel Barthelmes Richard J Walton Jennifer J Arnold Ian L McAllister Judy M Simpson Anna Campain Alex P Hunyor Robyn Guymer Rohan W Essex Nigel Morlet Mark C Gillies

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