Attaining consistent robust engraftment in the structurally normal liver is an obstacle for cellular transplantation. Most experimental approaches to increase transplanted cells' engraftment involve recipient-centered deleterious methods such as partial hepatectomy or irradiation which may be unsuitable in the clinic. Here, we present a cell-based strategy that increases engraftment into the st...

This paper devotes a novel micellar structure for cancer theranostics by incorporating magnetic and therapeutic functionalities into a natural sourced targeting polymer vehicle. Heparin-folic acid micelles taking advantage of both excellent loading capability and cancer targeting ability have been employed to simultaneously incorporate superparamagnetic iron oxide nanoparticles (SPIONs) and dox...

The localization of microbubbles to a treatment site has been shown to be essential to their effectiveness in therapeutic applications such as targeted drug delivery and gene therapy. A variety of different strategies for achieving localization has been investigated, including biochemical targeting, acoustic radiation force, and the incorporation of superparamagnetic nanoparticles into microbub...

Interlocking nailing is a common surgical operation to stabilize fractures in long bones. One of the difficult parts of the surgery is how to locate the position and direction of a screw hole on the interlocking nail, which is invisible to the naked eye after insertion of the nail into the medullary canal. Here, we propose a novel two-stage targeting process using two passive magnetic devices t...

Magnetic iron oxide nanoparticles (IONPs) are one of the most extensively studied materials for theranostic applications. IONPs can be used magnetic resonance imaging (MRI), delivery therapeutics, and hyperthermia treatment. Silk is a biocompatible material biomedical Previously, we produced spheres made H2.1MS1 bioengineered silk that specifically carried drug to Her2-overexpressing cancer cel...

Personalized Medicine In article 2203120 by Daniele De Pasquale, Carlotta Pucci, Gianni Ciofani, and co-workers, patient-derived cancer cell membrane-coated magnetic/lipid nanovectors allow for a precise personalized targeting against glioblastoma multiforme cells. The combination of magnetic hyperthermia chemotherapy, the latter selected based on patients' response, improve antitumor efficacy,...