Purpose. Malignant rhabdoid tumor (MRT) is an uncommon tumor that rarely occurs outside of renal and central nervous system (CNS) sites. Data from the literature were compiled to determine prognostic factors, including both demographic and treatment variables of malignant rhabdoid tumor, focusing on those tumors arising in extra-renal, extra-CNS (ER/EC MRT) sites. Patients and Methods. A system...

SMARCB1 is deleted in rhabdoid tumor, an aggressive paediatric malignancy affecting the kidney and CNS. We hypothesized that the oncogenic pathway in rhabdoid tumors involved epigenetic silencing of key cell cycle regulators as a consequence of altered chromatin-remodelling, attributable to loss of SMARCB1, and that this hypothesis if proven could provide a biological rationale for testing epig...

introduction: different imaging modalities are used to evaluate salivary gland diseases, including tumors. ultrasonography (us) is the preferred method on account of its ease of use, affordability, safety profile, and good tolerance among patients. the aim of this study was to evaluate the role of us in differentiating malignant from benign parotid tumors, in the context of previous controversy...

Primitive neuroectodermal tumor (PNET) / medulloblastoma (MB) are the most common malignant central nervous tumors of the first decade of life. Atypical teratoid / rhabdoid tumor (ATT / RT) is a tumor of infancy and childhood although occasional cases have also been described in adults. ATT/RT has a characteristic histopathological, immunocytochemical and ultrastructural features. ATT /RT is a ...

The sarcomatoid variant of hepatocellular carcinoma (HCC) is a rare histologic variant comprising malignant spindle cells and typical HCC. The proportion of the spindle cell component varies; when the tumor fully consists of malignant spindle cells, it is difficult to distinguish from various primary sarcomas. The 2010 World Health Organization classification of gastrointestinal tract tumors cl...

Abstract Atypical teratoid/rhabdoid tumors (AT/RTs) of the central nervous system (CNS) are rare, aggressive, early childhood with unfavorable prognosis. There have been 31 cases reported children AT/RT CNS and extra primary tumors. In addition to its aggressive tendencies, malignant rhabdoid (MRTs) kidney also shown a common genetic abnormality-inactivating mutation SMARC B1/INI-gene. We repor...