A new cyclic dipeptide, petrocidin A (1), along with three known compounds-2,3-dihydroxybenzoic acid (2), 2,3-dihydroxybenzamide (3), and maltol (4)-were isolated from the solid culture of Streptomyces sp. SBT348. The strain Streptomyces sp. SBT348 had been prioritized in a strain collection of 64 sponge-associated actinomycetes based on its distinct metabolomic profile using liquid chromatogra...

The pancreas plays an important role in the homeostasis of zinc (Zn), a nutritionally essential metal. In several previous studies, Zn ions induced inflammatory changes exocrine pancreas; however, little is known about complexes. this study, we microscopically, immunohistochemically, and ultrastructurally examined pancreatic lesions Sprague-Dawley (SD) rats by 4-week repeated oral dose toxicity...

iron overload is a clinical problem which can be prevented by using iron chelating agents. an alternative method of relieving iron overload is to reduce iron absorption from the intestine by administering specific iron chelating agents, which can bind iron to form nonabsorbable complexes. based on this strategy, a series of polymeric ligands containing the chelating moiety 3-hydroxypyridin-4-on...

a range of iron bidentae ligands containing the chelating moiety 3-hydroxypyridin-4-ones (hpos) have been synthesized via a single or a three-step synthetic pathway. in the single-step reaction, maltol was directly reacted by suitable primary amine and in the second synthetic method; benzylated maltol was reacted with related amines to give 1-substuted-2-methyl-3-benzyloxypyridin-4-one derivati...

introduction: due to the cell labeling potentials of various metal-maltol complexes, the idea of developing a possible cell labeling imaging agent using single photon emission computed chromatography (spect) with[111in]-maltolate complex has been investigated. methods: [111in] labeled 3-hydroxy-2-methyl-4h-pyran-4-onate ([111in]-maltolate) was prepared using freshly prepared [111in]incl3 and ...

BACKGROUND The chemical constituents of Panax ginseng are changed by processing methods such as steaming or sun drying. In the present study, the chemical change of Panax ginseng induced by steaming was monitored in situ. METHODS Samples were separated from the same ginseng root by incision during the steaming process, for in situ monitoring. Sampling was sequentially performed in three stage...

Volatiles emitted by the host's food would be the first signals used by parasitoids in the host location process and are thought to play an important role in host habitat location. In this study, the olfactory responses of Theocolax elegans (Westwood), a Pteromalid wasp that parasitizes immature stages of stored-product insect pests developing inside cereal or leguminous grains, to volatiles em...