Human services, such as social supports and health care, have low contractibility; services are difficult to specify measure, manage when delivered by a third party. Services can do fail, resulting in the inefficient use of public resources potential harm clients. This article develops conceptual framing using transaction cost economics (TCE) theory understand why human contract, management con...

System engineering is one of the most powerful tools for comprehensive project management and control. This tool emphasized the life cycle of the projects, manages every single activity and helps manage the main elements of the project through a set of management and engineering processes. The goal of the current study is to use a system engineering approach in design phase in order or to meet ...

Filtration through the kidney eliminates toxins, manages electrolyte balance, and controls water homeostasis. Reabsorption of water from the luminal fluid of the nephron occurs through aquaporin-2 (AQP2) water pores in principal cells that line the kidney-collecting duct. This vital process is impeded by formation of an "actin barrier" that obstructs the passive transit of AQP2 to the plasma me...

Ascites related to metastatic colorectal cancer (mCRC) reduces patient survival and quality of life, and systemic chemotherapy is largely ineffective for managing ascites. Here, we examined the clinical efficacy of intraperitoneal (IP) ziv-aflibercept for managing refractory ascites in 15 mCRC patients who did not respond to standard chemotherapy. Fifty or 100 mg of ziv-aflibercept in 100 mL of...

In the model eukaryote Saccharomyces cerevisiae, it has long been known that a functional trehalose pathway is indispensable for transitions to high glucose conditions. Upon addition of glucose, cells with a defect in trehalose 6-phosphate synthase (Tps1), the first committed step in the trehalose pathway, display what we have termed an imbalanced glycolytic state; in this state the flux throug...

Image segmentation is the procedure of the subdivision of a picture into its constituent districts or items. The aftereffect of Image segmentation is an arrangement of sections that all in all cover the whole picture or an arrangement of shapes separated from the picture. Each of the pixels in a district is comparable regarding some trademark or processed property, for example, shading, power o...

GALEN is developing a Terminology Server to support the development and integration of clinical systems through a range of key terminological services, built around a language-independent, re-usable, shared system of concepts--the CORE model. The focus is on supporting applications for medical records, clinical user interfaces and clinical information systems, but also includes systems for natu...