In this article we consider the technological change that has occurred in complex manufacturing systems within the past two decades and the implications it has had on the role of human operators in manufacturing systems control. Our examination ranges from the traditional production line manned by skilled machinists to flexible manufacturing systems (FMS) under supervisory control. On the basis...

Guaifenesin, a highly water-soluble active (50 mg/mL), classified as a BCS class I drug.Owing to its poor flowability and compressibility, formulating tablets especially high-dose one,may be a challenge. Direct compression may not be feasible. Bilayer tablet technology appliedto Mucinex®, endures challenges to deliver a robust formulation. To overcome challengesinvolved in bilayer-tablet manufa...

Guaifenesin, a highly water-soluble active (50 mg/mL), classified as a BCS class I drug.Owing to its poor flowability and compressibility, formulating tablets especially high-dose one,may be a challenge. Direct compression may not be feasible. Bilayer tablet technology appliedto Mucinex®, endures challenges to deliver a robust formulation. To overcome challengesinvolved in bilayer-tablet manufa...

background: every year many organizations formulate a code of ethics (coe) but when it comes to implementing, it does not achieve the desired purposes. ineffectiveness of coes can stem from different factors and surely, one of them is bad formulation. this research was conducted to identify the barriers to effective formulation of coes in one of the main state universities of medical sciences i...

In a manufacturing environment where a robotic arm is programmed to follow a specified trajectory such as in welding, painting, and soldering, it is often the case that the arm reaches a singular configuration, where the program is stopped, the arm is switched to a new configuration, and the motion is continued. This difficulty has been a long standing problem. This paper presents a mathematica...

Integrated scheduling and control is a new approach that seeks to unify the objectives of the various layers of optimization in manufacturing. Recent efforts in this field have used a continuous-time, slotbased formulation. This work investigates combining scheduling and control using a novel discrete-time formulation, utilizing the full process model through the entire horizon. This discrete-t...

Understanding the formulation and manufacturing parameters that lead to higher energy density longevity is critical designing energy-dense graphite electrodes for battery applications. A limited dataset includes 27 different formulation, protocols, performance properties reported. Input from are varied: slurry composition, mixing protocol, electrode coating gap size, drying temperature, speed, ...