Rather than focusing on his many scientific successes, Peter Kim, PhD, a biochemist known for his innovative work in developing and shepherding drugs to market, chose instead to tell the School of Medicine’s graduating class of 2016 about one of his key failures. “The greatest scientific failure in my career was when I had to stop a clinical trial of a vaccine for HIV/AIDS. And it came just as ...

More and more, databases are combined using record linkage methods to increase the amount of available information. When there is no unique identifier to perform the matching, a probabilistic linkage is used. A record on the first file is linked to a record on the second file with a certain probability, and then a decision is made on whether this link is a true link or not. This process usually...

Application Layer Multicast (ALM) is an alternative to IP multicast, which has yet to achieve a widespread deployment in the Internet. ALM places multicast primitives directly in the multicast members, i.e. end systems, which use an overlay topology on top of the physical network for multicasting. The overlay consists of unicast connections between the members, hence bypasses the need for multi...

Supporting multi-point group communications in network management platforms is essential for improving scalability and responsiveness of management applications. With the deployment of IP multicasting as the standard infrastructure for multi-point group communications in the Internet, the integration of IP multicasting in SNMP becomes signi cantly important to achieve these goals. This paper pr...

Without a doubt, multicast communication|the one-to-many or many-to-many delivery of data|has become a hot topic. It is of interest in the research community, among standards groups, and to network service providers. For all the attention multicast has received, there are still issues that have not been completely resolved. One result is that protocols are still evolving and some standards are ...

Many business organizations generate a huge amount of transaction data. Association rule mining is a powerful analysis tool to extract the useful meanings and associations from large databases and many automated systems have been developed for mining association rules. However, most of these systems usually mine many association rules from large databases and it is not easy for a user to extrac...

BACKGROUND Hyperthermia is considered an efficient complement in the treatment of head and neck squamous cell carcinoma (HNSCC). Hyperthermia induces cell apoptosis in a temperature- and time-dependent manner. However, the molecular mechanism of hyperthermia remains unclear. The aim of this study was to investigate the mechanism of apoptosis induced by ultrasound hyperthermia in HNSCC cell line...