Advances in our understanding of stem cell interactions with their environment are leading to the development of new materials-based approaches to control stem cell behavior toward cellular culture and tissue regeneration applications. Materials can provide cues based on chemistry, mechanics, structure, and molecule delivery that control stem cell fate decisions and matrix formation. These appr...

Design paradigm exactly addresses the higher-level design issues where the implementation field (mechanical, electrical etc.) of the product is left for later stages. Once the general design problem is understood, better products will be emerging; especially products requiring a cooperation of various engineering-field components are a bigger concern. The idea is that design is a phenomenon, cu...

We present a novel approach for optimizing acoustic parameters using sensitivity analysis for computer-aided design and analysis of architectural models. Our approach builds on recent low-dispersion wave-based acoustic solvers that can accurately compute the pressure field in large models. We present an efficient technique to compute the gradient of the pressure field using automatic differenti...

Metamaterials are engineered materials with unusual, unique properties and advanced functionalities that a direct consequence of their microarchitecture. While initial were limited to optics electromagnetism, many novel categories metamaterials have applications in different areas research practice, including acoustic, mechanics, biomaterials, thermal engineering, appeared the last decade. This...