We used flow cytometry to measure the expression of human mela noma antigens on cell suspensions dissociated from metastatic masses. The objective was to study the heterogeneity between tumor samples from different patients and between different tumors excised from a single patient. Fifty-three métastasesexcised from 34 melanoma patients »ere analyzed with a panel of nine murine monoclonal an...

Sustainable development is a Controversial concept which has been considered over the three decades. It is comprehensive development and includes all of dimensions as “economic’’, “social’’ and ‘‘environmental’’. In economic objective, it requires substantial economic change that can be brought about by investment and trade. They are effective factors of sustainable developm...

semantics: k-CFA ((f e), β̂, σ̂, â) ; (e′, β̂′, σ̂′, â′), where Ê(f, β̂, σ̂) ∋ 〈(λ (x) e′), β̂′′〉 â′ = ⌊l · â⌋k Ê(e, β̂, σ̂) = d̂ β̂′ = β̂′′[x 7→ â′] σ̂′ = σ̂ ⊔ [â′ 7→ d̂] And: Ê(x, β̂, σ̂) = σ̂(β̂(x)) Ê((λ (x) e), β̂, σ̂) = {〈(λ (x) e), β̂〉} Resolving and Exploiting the k-CFA Paradox, New England Programming Language and Systems Sysmposium, MIT, December, 2009 – p.5/22 The Paradox of k-CFA Resolving and Exploiting ...

Background—Inflammatory bowel disease (IBD) is a chronic inflammation of the gastrointestinal tract caused by an abnormal and uncontrolled immune response to one or more normally occurring gut constituents. Aim—Given the eVects of transforming growth factor â1 (TGF-â1) on both the immune system and extracellular matrix, we postulated that alterations in TGF-â signalling in intestinal epithelial...

A number of reports have described the occurrence of liver cell adenomas in women using oral contraceptives. Circum stantial evidence derived from human and early experimental animal data, together with the recent report of Taper [Cancer (Phila.), 42: 462-467, 1978], suggests that oral contraceptive steroids may be liver tumor promoters. The objective of this study was to determine whether the ...

The years 1895 to 1898 were momentous for their impact on health and human well beings. First, Wilhelm Roentgen noted a glowing fluorescent screen, caused by invisible rays. This event subsequently led to the discovery of X-rays in 1895, and thus the birth of the “atomic age”. Next Becquerel’s investigations of these mysterious rays led to his experiments with uranium salt crystals. He th...

â â â â â  â  in this paper, we address the question that does fdi alone affect economic growth or interaction of fdi and human capital is required to boost economic growth. we develop the model with an expanding variety of products. we estimate the model using some advanced tests utilizing data on fdi flows from developed countries. we find stronger complementary effects between fdi and human ...

The efficacy of present day antineoplastic regimens depends upon the delivery and penetration of therapeutic agents through the tumor vas cular and interstitial spaces to the tumor cell target. The distribution of relevant molecules or cells in a solid tumor is often poor and heteroge neous and is believed to be due to a number of pathophysiological factors, including elevated interstitial flui...

Methotrexate reduces intracellular pools of 5-methyltetrahydrofolate and could result in reduced conversion of homocysteine to methionine by methionine synthetase. This study was designed to investigate the effects of moderate dose to very high dose methotrexate on methionine and total homocysteine as reflections of methotrexate induced intracellular events. Methionine and total homocysteine we...

Ú ̆ ‰ ‡ Ï , È Â ‡ · was an active, if not the most active, character throughout „ Â „ ’s reign. However, the character of È Â ‡ · and his brothers is foggy and puzzling. Although many of us have been taught to classify figures in Tanach into the roles of either ¢ ˆ „ È ̃ ¢ or ¢ ̄ ̆ Ú ¢ to further our understanding of the manifest context © Ù ̆ Ë ® and latent meaning © „ ̄ ̆ ® of the text, È Â ‡ · and ...