The goal of this study was to determine the effects of the L-type calcium channel blockers verapamil and diltiazem on the currents of voltage-gated potassium channel (fKv1.4ΔN), an N-terminal-deleted mutant of the ferret Kv1.4 potassium channel. Measurements were made using a two electrode voltage clamp technique with channels expressed stably in Xenopus oocytes. The fKv1.4ΔN currents displayed...

protein aggregation is a problem in biotechnology. high temperature is one of the most important reasons to enhance enzyme inactivation and aggregation in industrial systems. this work focuses on the effect of tio2 and sio2 nanoparticles on refolding and reactivation of lysozyme. in the presence of tio2 and sio2 nanoparticles, after enzyme heat treatment at 98◦c for 30 min, not only aggregates ...

This study presents the first report on enhanced bacterial inactivation of E. coli by RF-plasma pretreated cotton with high-surface-area CuO powders compared with nonpretreated cotton textiles. The high-surface-area CuO (65 m/g) powder was fully characterized. The E. coli inactivation proceeded in the dark and was accelerated under visible and sunlight irradiation even at very low levels of vis...

the lethality of pulsed ultra-violet (uv) rich light for the inactivation of pathogenic bacteria has been investigated. a low pressure xenon filled flash lamps that produced uv intensities have been used. the pulsed operation of the system enable the release of electrical energy stored in the capacitor into the flash lamp within a short time and produces the high current and high peak power req...

A probabilistic model was used to compare cryoprecipitate to viral inactivated, commercial fibrinogen concentrate to evaluate with regard to the recipient's risk of exposure to an emergent AIDS-like epidemic. In patients who occasionally need a therapeutic dose of fibrinogen, commercial fibrinogen would be marginally safer than cryoprecipitate if the new pathogen were sensitive to inactivation....

This study aims to explore the potential use of electro-oxidation (EO) as a decentralized wastewater treatment method. The simulated comprising bacterial consortium was treated by employing mixed metal oxide (MMO). In particular, lab-scale batch electrooxidation reactor used at different operating parameters including NaCl dose (n), current density (j), and time (t) in order optimize process us...

BACKGROUND: Ultraviolet reactors that are used for drinking water disinfection need to be tested to ensure they are delivering the required doses and achieving the desired level of pathogen inactivation to protect public health. Testing methods can use biological, chemical, or particle surrogates, although not all approaches have been approved for reactor validation. The non-pathogenic bacterio...