hydatid disease is caused by the larva of echinococcus granulosus parasite. mebendazole (mbz) is used as an alternative choice for the treatment of the disease. aspartate aminotransferase (ast) is an essential enzyme in amino acid metabolism. the aim of the present study is to evaluate the effect of mbz on ast activity of hydatid cyst parasite in order to detect enzymatic parameter for drug eff...

Changes in the sensitivity of Trichinella spiralis to anthelmintic treatment during the first 3 days of infection in mice were studied. Oral administration of either mebendazole or albendazole at 6.25 mh/kg 2 hr after exposure to infection eliminated 95-100% of the worms as determined at necropsy on day 7 postinoculation. Beyond the first day of infection the sensitivity of the parasite to benz...

Malnutrition, anaemia, and gut parasites are commonly interrelated. Using the Nippostrongylus brasiliensis-rat model, the effect of iron and protein deficiency on the efficacy of benzimidazole anthelmintics was studied. It was demonstrated that the anthelmintics mebendazole and fenbendazole were significantly less effective in eradicating parasites when animals were deficient in iron and protei...

Accepted 17 July 1996 A 36-year-old man was admitted to this unit with almost complete quadriplegia with no sensory level. The bladder and bowel functions had remained intact. When he was a 20-year-old student he had presented with brachialgia and neck swelling, which had been aspirated percutaneously in India in 1980; the fluid was discovered to contain protoscolecs and he was given a full cou...