We hypothesized that the deoxygenation-induced increase in cation permeability of sickle cells was related to mechanical distention of the membrane by growing HbS polymer within the cell. To test this hypothesis, we determined the effect of deoxygenation on cation fluxes in sickle cells under conditions that restricted or permitted extensive growth of polymer, producing different degrees of mem...

Micropipette aspiration was used to test mechanical strength and water permeability of giant-fluid bilayer vesicles composed of polyunsaturated phosphatidylcholine PC lipids. Eight synthetic-diacyl PCs were chosen with 18 carbon chains and degrees of unsaturation that ranged from one double bond (C18:0/1, C18:1/0) to six double bonds per PC molecule (diC18:3). Produced by increasing pipette pre...

A new type of reinforcement for unidirectional natural fiber composites has been developed, where a paper layer is assembled with a layer of unidirectional flax yarns. The paper layer chemically and mechanically bonds to the loose yarns to maintain their alignment and enables better manipulability of the reinforcement during stacking in the mold. Unfortunately, the paper layer adversely affects...

The stiffness and hydraulic permeability of soft contact lenses may influence its clinical performance, e.g., on-eye movement, fitting, and wettability, and may be related to the occurrence of complications; e.g., lesions. It is therefore important to determine these properties in the design of comfortable contact lenses. Micro-indentation provides a nondestructive means of measuring mechanical...

The use of impacted, morsellised bone grafts has become popular in revision total hip arthroplasty (THA). The initial stability of the reconstruction and the effectiveness of any subsequent process of revitalisation and incorporation will depend on the mechanical integrity of the graft. Our aim in this study was to document the time-dependent mechanical properties of the morsellised graft. This...

Mechanical ventilation (MV) and ventilator strategies can induce or aggravate lung injury and may contribute to the development of distant organ failure, including the gastrointestinal tract. A retrospective cohort study was performed among 61 preterm infants, with a gestational age of 25-36 weeks, admitted at a neonatal intensive care unit. Intestinal permeability was measured by the sugar abs...