ACP (amorphous calcium phosphate) and DCPD (dicalcium phosphate dihydrate, or Brushite) powders were high energy dry ball milled at a 1:1 ratio for 1, 2, 3, 4, 10, or 24 hours to produce a variety of powders for use as calcium phosphate cements (CPC). A 1:1 blend of powders not subjected to milling was used as baseline material (control). Physicochemical and mechanical characterization was perf...

Recent findings suggest that itch produced by intradermal insertion of cowhage spicules in human is histamine independent. Neuronal mechanisms underlying nonhistaminergic itch are poorly understood. To investigate which nerve fibers mediate cowhage induced itch in man, action potentials were recorded from cutaneous C-fibers of the peroneal nerve in healthy volunteers using microneurography. Mec...

The synthesis, chemical and photophysical investigation of a series eight novel copper-halide derivatives with different nuclearity is herein presented. One mononuclear copper(I) complex formula [CuI(pyridine)(P)2], where P functionalized phosphine, six dinuclear bearing the rhombic {Cu2I2} subunits general [Cu(?-I)(P)(N)]2 (N = pyridine, quinoline 4-cyanopyridine) as well one tetranuclear copp...

Articular cartilage exhibits complex mechano-electrochemical behaviour due to its anisotropy, inhomogeneity and material non-linearity. In this work, the thickness and radial dependence of cartilage properties are incorporated into a 3D mechano-electrochemical model to explore the relevance of heterogeneity in the behaviour of the tissue. The model considers four essential phenomena: (i) osmoti...

In the fern Adiantum capillus-veneris, chloroplast movement is induced by mechanical stimulation as well as by light stimulation. Directional movement of both types depends on an actin-based motile system. To investigate the physiological relationship between mechanical and light signaling in the regulation of chloroplast movement, we examined the mechano-response of chloroplasts whose motility...