Estrogens are widely used in hormone replacement therapy, gynecology, urogynecology and rarely in dermatology. Non-therapeutic use of estrogens is very widespread. Estrogens are used as contraceptives, which cause a lot of serious side effects. A common clinical problem is skin hyperpigmentation (melasma), occurring mainly in women who take contraceptives with high doses of estrogens. But low d...

melasma is a common acquired skin disorder. while different treatments are currently being used, in many cases it is refractory to treatment. according to the effects of topical steroids in decreasing skin pigmentation, we studied the efficacy of this new method for treatment of melasma. a total of 42 women with facial melasma, admitted to the department of dermatology of hamadan, were enrolled...

introduction: ablative and nonablative lasers have been used to treat melasma. we aimed to assess and compare the combining q-switched nd:yag laser (qsnyl) and fractional erbium:yag laser (feyl) with qsnyl alone in treatment of melasma. methods: this randomized controlled clinical trial was performed in our research center during 2013-2014. women with melasma and without a history of keloid for...

Background: Melasma is a pattern of facial pigmentation that affects upper lip, cheeks, forehead and chin. The disease is seen mainly in 30-55 year old women, and may be regarded as a physiological change in pregnancy. Its etiologic nature is still unknown. Objective: To determine the prevalence of melasma in women in Ardebil city. Patients and Methods: The study was cross sectional-descr...

Background and aim: Melasma is an acquired, symmetric hyperpigmentation, specially in sun-exposed skin. Disorders of thyroid gland result from processes that stimulate the overproduction or underproduction of thyroid hormones. This study was performed to assess the association of melasma with thyroid disorders.Materials and Methods: This case-control study was performed...

ABSTRACT Background: Melasma, a common dermatological problem which has no standard recommended therapy. This study aimed to compare the clinical efficacy of combined trichloroacetic acid peel and ascorbic with alone in epidermal melasma. Methods: A quasi-experimental was conducted on 148 patients melasma, dermatology department Pak Emirates Military Hospital, Rawalpindi from August 2019 Januar...

BACKGROUND Melasma is an acquired disorder of hypermelanosis of great psychosocial concern. The treatments with various conventional therapies are often unsatisfactory. Lasers and light sources have been used to treat pigmented lesions, but in Asian skin with higher melanin content, such treatments may be challenging. OBJECTIVES To determine the effectiveness of treating melasma with a combin...

Melasma is an acquired symmetric hypermelanosis characterized by irregular light-to gray-brown macules and patches on sun-exposed areas. Many therapeutic agents are available but are unsatisfactory. Recently, it has been demonstrated that lincomycin (LM) and linoleic acid (LA) can inhibit melanogenesis in vitro. Our purpose was to investigate the clinical efficacy of topical application of LM a...

Melasma is a common disorder affecting a significant percentage of the population, particularly those with skin of color. Therapy with hydroquinone, a depigmenting agent, as a single agent or in combination with other agents has been used with variable success. A triple-combination (TC) cream combining hydroquinone 4% with tretinoin 0.05% and fluocinolone acetonide 0.01% was developed for the t...