Melasma is an acquired, chronic, and symmetrical hypermelanosis, characterized by brown patches of variable darkness on sun exposed areas of body. There are numerous modalities of treatment currently in use for this disease, of which the chemical peeling is very commonly used. Therefore, the present work was done to see the effect of 82% lactic acid peel in the treatment of melasma. A total num...

BACKGROUND In recent times, tranexamic acid (TA) is claimed to have whitening effects especially for ultraviolet-induced hyperpigmentation including melasma. The aim of our study was to evaluate the efficacy and safety of topical solution of TA and compare it with combined solution of hydroquinone and dexamethasone as the gold standard treatment of melasma in Iranian women. MATERIALS AND METH...

Melasma has significant emotional and psychological effects. These repercussions can be measured using general measures of skin disease. SKINDEX-16 was used in a pilot study (1) to show a significant impact on health-related quality of life (HRQoL) and a correlation with disease severity measured by MASI (Melasma Area Severity Index) (2). A melasma-specific scale, the Melasma Quality of Life Sc...

R ecent data show that melasma lesions have, in addition to increased pigmentation, more elastosis and vascularization than perilesional skin. The stabilized formulation of Kligman preparation has shown significant improvements in the treatment of melasma. However, most of the treatments only target the pigmentation, and none of them has been demonstrated so far to prevent the frequent relapses...

purpose: to analyze the clinical patterns and etiologies of uveitis in isfahan. methods: the records of 2016 patients with uveitis who had been referred to the feiz tertiary eye care center, isfahan, between 1999 and 2013 were classified and analyzed with respect to demographic, clinical, anatomical, and etiological characteristics. results: at the onset of uveitis, the mean patient age was 33....

Background: Melasma is a common hyperpigmentation disorder that has a significant effect on an individual’s quality of life. However, there is no preference-based measurement that reflects quality of life in patients with melasma. Objectives: To assess the impact of melasma on quality of life by using a health status measurement – the Dermatology Life Quality Index (DLQI) – and a preferencebase...

BACKGROUND Melasma is a common hyperpigmentation disorder that has a significant effect on an individual's quality of life. However, there is no preference-based measurement that reflects quality of life in patients with melasma. The objective of this study was to assess the impact of melasma on quality of life by using a health status measurement - the Dermatology Life Quality Index (DLQI) - a...

BACKGROUND Melasma is a common pigmentary disorder that affects all skin types but is seen more in individuals with Fitzpatrick skin type IV to VI. Safe and effective treatment options for melasma need to be explored. Already proven effective for the treatment of pigmentary disorders, lasers have been used to treat melasma in recent years. OBJECTIVE To evaluate the efficacy and safety profile...

Melasma is an irregular brown or grayish-brown facial hypermelanosis, often affecting women, especially those living in areas of intense UV radiation. The precise cause of melasma remains unknown; however, there are many possible contributing factors. Because of its dermal component and tendency to relapse, melasma is often difficult to treat. The use of broad-spectrum (UVA + UVB) sunscreen is ...