Quinine-associated thrombocytopenia and hemolytic uremic syndrome (with renal failure and microangiopathic red blood cell changes) is a recently described entity.',* I recently cared for a patient with a similar illness who developed varying degrees of leukopenia, thrombopenia, and renal failure after quinine ingestion. My patient had the incidental finding of Klinefelter's syndrome. Three of t...

A 30-year-old Caucasian man developed fever, myalgia, and dry cough that lasted for 3 weeks. He works as a house painter in Phoenix, Ariz. Three months later, he developed right-sided headache, meningismus, and photophobia. A lumbar puncture (LP) revealed normal opening pressure, lymphocytic pleocytosis (340 white blood cells, 96% lymphocytes), elevated cerebrospinal fluid (CSF) total protein (...

Purpose: To report the clinical spectrum of Vogt-Koyanagi-Harada (VKH) disease in North India. Methods: A retrospective review of VKH patients visiting the uveitis clinic of department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, between 2003 and 2012, was done. The diagnosis of VKH disease was established by criteria from the International Committee ...

Neurology 2012;78:849–850 For approximately 65 million people in the world with epilepsy, antiepileptic drugs (AEDs) are the mainstay of treatment.1 Lamotrigine (LTG) is a nonenzyme inducing AED with favorable pharmacokinetics, approved for use by the Food and Drug Administration (FDA) in epilepsy as well as bipolar disorder. From May 2009 to April 2010, approximately 9 million prescriptions we...

Background: Intraspinal bleeding especially in the form of subdural hematoma is rare in hemophiliacs. In the present case, we report a neglected hemophilic A child with such a problem and discuss its management options. Results : A 9-year old hemophilic A boy presented with quadriparesis, confusion and meningismus after a fall 4 days before admission. There was no sign of direct trauma to his b...