The mid-life period is a critical window for increases in body weight and changes in body composition. In this review, we summarize the clinical experience of the menopausal transition by obesity status, and examine the evidence regarding the menopausal transition and reproductive hormones effects on body weight, body composition, or fat distribution. Mid-life obesity is associated with a diffe...

BACKGROUND Dietary studies show a relationship between the intake of iron enhancers and inhibitors and iron stores in the general population. However, the impact of dietary factors on the iron stores of blood donors, whose iron status is affected by blood donations, is incompletely understood. STUDY DESIGN AND METHODS In the Danish Blood Donor Study, we assessed the effect of blood donation f...

BACKGROUND Although the association between menopause and cardiovascular disease (CVD) risk has been studied extensively, the simultaneous role of chronological aging herein remains underexposed. This study aims to disentangle the relationships of menopausal status and chronological aging with CVD risk factors in the largest study population to date. METHODS In this cross-sectional study, CVD...

BACKGROUND AND OBJECTIVES The aim of this study was to study the role of menopausal status and physical activity on quality of life. METHODS A total of 1,165 Finnish women aged 45-64 years from a national representative population-based study were followed up for 8 years. Study participants completed the Health 2000 study questionnaire and follow-up questionnaire in 2008. Ordinal logistic reg...

To investigate the clinical effects of EH0202, a Japanese herbal supplement, on the menopausal symptoms and physical status of peri- and post-menopausal women. Thirty-two post-menopausal women (53.0+/-5.1 years) presented with menopausal complaints were enrolled in the clinical study. Patients were administered an herbal supplement, EH0202 (6 g/day for 6 months), and were assessed for improveme...

Objectives The aims of the research are to examine the problems of abnormal menopausal women: the relationship between depression and menopausal-specific quality of life (MENQOL)-symptoms among postmenopausal women; the association of MENQOL-symptoms between pre- and postmenopausal female society in Bangladeshi real community. Methods This cross sectional study was conducted on 435 women of T...

PURPOSE The role of family history to the risk of breast cancer was analyzed by incorporating menopausal status in Hong Kong Chinese women, with a particular respect to the estrogen receptor-positive (ER+) type. METHODS Seven hundred and forty seven breast cancer incident cases and 781 hospital controls who had completed information on family cancer history in first-degree relatives (nature f...

OBJECTIVES The aim of this study was to assess the relationship between sex hormones and natriuretic peptide levels in community-based adults. BACKGROUND Women have higher circulating natriuretic peptide concentrations than men, but the mechanisms for these sex-related differences and the impact of hormone therapy are unclear. Experimental studies suggest that androgens may suppress natriuret...

BACKGROUND The search for biologic endpoints and biomarkers in the study of breast cancer risk assessment and risk reduction strategies has led to an interest in obtaining cytologic information and other biomarkers from nipple aspirate fluid (NAF). METHODS This descriptive study examined factors associated with an increased ability to obtain NAF in a cohort of 3043 women between the ages of 1...

Purpose: To study the relationship between (FDG) uptake expressed quantitatively as standardized uptake values (SUVs) in normal breast tissues and breast density, age, menopausal status determined during dual-time point FDGPET/CT imaging. Materials and Methods: maximum and average SUVs were determined in two hundred eighty four patients (all females; mean age 55.5 ± 14.1 range 13-84 years, 115 ...