Twelve control dogs receiving a single intravenous injection of mercuric chloride, 3.0 mg. per kg., all died within 4 to 11 days afterwards with marked nitrogen retention and extensive necrosis and calcification of the epithelium lining the proximal convoluted tubules. Three dogs of comparable age and weight were reduced to a standard hypoproteinemic state by repeated plasmapheresis. Each dog t...

Exposure to heavy metals may have toxic effects on several human organs causing morbidity and mortality. Metals trigger or exacerbate autoimmunity in humans. Inbred mouse strains with certain H-2 haplotypes are susceptible xenobiotic-induced autoimmunity; their immune response such as mercury, gold, silver been explored. Serum antinuclear antibodies (ANA), polyclonal B-cell activation, hypergam...

The order with respect to water in the solvolysis of cinnamoyl chloride in aqueous acetone and aqueous acetonitrile of lesser water content is H”2.6, favours an addion-elimination mechanism , S N 2 mechanism or a competition between them. Higher enthalpy and lower negative entropy of activation favours S N 2 mechanism. Order with respect to mercuric chloride in the concentration range of 0.001M...

In the present study, an efficient mercury-tolerant bacterial strain (RS-5) was isolated from heavy-metalcontaminated industrial effluent. Under shake flask conditions, 97% of the supplemented mercuric chloride was sequestered by the biomass of RS-5 grown in a tryptone soy broth. The sequestered mercuric ions were transformed inside the bacterial cells, as an XRD analysis of the biomass confirm...

Aerobic cometabolism of cis-1,2-dichloroethylene (c-DCE) by a butane-grown mixed culture was evaluated in batch kinetic tests. The transformation of c-DCE resulted in the coincident generation of c-DCE epoxide. Chloride release studies showed approximately 75% oxidative dechlorination of c-DCE. Mass spectrometry confirmed the presence of a compound with mass-to-charge-fragment ratios of 112, 83...

1. Serial changes in plasma renin activity and plasma angiotensin levels were followed in rats during acute renal failure induced by mercuric chloride or glycerol. 2. During mercuric chloride-induced acute renal failure there were transitory large increases in plasma renin and angiotensin. In contrast, rats with acute renal failure produced by glycerol had a reduction in plasma renin and angiot...

The use of mercuric chloride as an histological fixative was associated with high environmental atmospheric concentrations of mercury vapour (up to 0-5 nmol/l) as well as mercury compounds (total Hg to 1-0 nmol/l). Technicians exposed to this environment showed increased urinary mercury (median value 265 nmol/24h) and protein outputs (median value 117 mg protein/24h). Routine control measures, ...

Mercuric reductase, a cytosolic flavoprotein which catalyzes the NADPHdependent reduction of mercuric ion to metallic mercury, has been purified about 82-fold from Klebsiella pneumoniae cells and kinetic properties were investigated. The purification method consisted of rapid (two-step) and straightforward procedure involving dye matrix affinity chromatography. The freshly native protein exhibi...

Smith, P. B. (Communicable Disease Center, Atlanta, Ga.). Growth of staphylococci on mercuric chloride agar. J. Bacteriol. 84:1016-1019. 1962.-An attempt has been made to corroborate a report that "epidemic" strains of staphylococci are more resistant to mercuric salts than are "nonepidemic" strains. A comparison of mercury resistance with coagulase production and phage type or pattern of 493 s...