the importance of mesenchymal stem cells (mscs), as adult stem cells (ascs) able to divide into a variety of different cells is of utmost importance for stem cell researches. in this study, the ability of cartilage extract to induce differentiation of rat derived omentum tissue mscs (rot-mscs) into chondrocyte cells (ccs) was investigated. after isolation of rot-mscs, they were co-cultured with...

rabbits have the capacity to regenerate holes in their ears by forming a blastema, a tissue that is made up of a group of undifferentiated cells. the purpose of the present study was to isolate and characterize blastema progenitor cells and compare them with marrow mesenchymal stem cells (mscs). five new zealand white male rabbits were used in the present study. a 2-mm hole was created in the a...

conclusions according to the results of the present study, it can be concluded that adipose derived mscs can be cultured in serum-free media with no change in their differentiating capacity. this finding gives us a hope for future cell therapy studies and trials with little concern about zoonotic infections or immunological reaction. results the isolated cells showed adherent spindle shaped mor...

introduction: failure of human body tissue and organs is believed to be one of the most important health problems all over the world. the great challenge for tissue engineers is to optimize suitable systems to separate, proliferate and differentiate the cells so that they can set out to create tissue by a harmonic 3-d growth. therefore, the tissue engineers must provide an environment like the ...

introduction: various neuroregenerative procedures have been recently employed along with neurorehabilitation programs to promote neurological function after spinal cord injury (sci), and recently most of them have focused on the acute stage of spinal cord injury. in this report, we present a case of acute sci treated with neuroprotective treatments in conjunction with conventional rehabilitati...

Stem cell research has obtained much prominence in recent years for its therapeutic potential in dealing with serious diseases, many of which are essentially incurable by routine therapies. Mesenchymal stem cells with pluripotency and immunomodulatory properties are suitable candidates for tissue engineering and regenerative medicine. Today, nanofibrous scaffolds are widely used in tissue en...

background infertility is a serious social problem in advanced nations, with male factor in half of all cases of infertility. this study was conducted to determine the regenerative effect of bone marrow-derived stem cells in spermatogenesis of infertile hamster. methods twelve adult male hamsters were equally divided into azoospermic and control groups. busulfan was intraperitoneally used for i...

objective(s):in previous investigations, we have shown para-nonylphenol (p-np) caused significant reduction of proliferation and differentiation of rat bone marrow mesenchymal stem cells (mscs) in vitro. in this study, we first treat the rats with p-np, then carried out the biochemical and morphological studies on mscs. materials and methods: proliferation property of cells was evaluated with t...

objective(s): mesenchyme is a type of undifferentiated loose connective tissue that is derived mostly from mesoderm. recently, mesenchymal stem cells (mscs), as adult stem cells (ascs) able to divide into a variety of different cells, are of utmost importance for stem cell research. in this research, ability of the liver extract to induce differentiation of rat derived omentum tissue mesenchyma...

bone marrow mesenchymal stem cells can differentiate into neurons and astrocytes after transplantation in the spinal cord injury of rats. although bone marrow mesenchymal stem cells are known to protect against spinal cord injury through anti-apoptotic effects, but generation of neural stem cells with large number and safety protocols unclear. in the present study, described the differentiation...