It is unclear whether the SDA long-term morbidity results (10) are coherent with mortality results. Among individuals who were symptom-free at the start of the study, there was an association between increased symptoms and PM. These risk estimates were 40-fold greater than those estimated for smoking. There were no analyses presented for those individuals who had symptoms at the start of the st...

Controversy exists concerning the fetal risk associated with exposure to low-dose methylmercury from maternal fish consumption. Previous studies of the effects of acute prenatal mercury exposure identified delays in achieving developmental milestones among exposed children. This led to public health concern that prenatal low-dose exposure from fish consumption could adversely affect the fetus. ...

Mercury is a major issue in environmental health, as it can be biotransformed to methylmercury, accumulate into aquatic organisms, and enter the food chain. Therefore, we searched for molecular markers for methylmercury exposure comparing, by differential display, exposed Xenopus embryos to controls. We found two genes whose expression is completely inhibited by CH3HgCl, and we propose them as ...

OBJECTIVE Emerging in vitro and animal evidence suggests that methylmercury could increase type 2 diabetes, but little evidence exists in humans. We aimed to prospectively determine associations of mercury exposure, as assessed by biomarker measurement, with incident diabetes. RESEARCH DESIGN AND METHODS We used neutron activation analysis to measure toenail mercury, an objective biomarker of...

NHANES subjects self-identified as "Asian, Pacific Islander, Native American, or multiracial" (A/P/N/M) have higher levels of blood organic mercury than other racial/ethnic groups; however, the reasons for this have been unclear. This research uses exposure modeling to determine the reasons for elevated blood methylmercury (MeHg) levels, and also extends previous analyses of observed NHANES blo...