The periodontal disease is a chronic, degenerative disease which is localised on the gingiva, periodontal ligament, cementum and alveolar bone. The main etiological factor is oral biofilm with microorganisms. The search for the pathogens of periodontal diseases has been underway for more than 100 years, and continues up today. The currently recognized key Gram negative periodontopathogens inclu...

BACKGROUND/AIM The purpose of the present investigation was to examine subgingival microbial profiles associated with refractory periodontitis and to seek such profiles in periodontally healthy, periodontally well-maintained elder and untreated periodontitis subjects. METHODS 36 subjects were defined as refractory on the basis of further attachment loss after scaling and root planing, surgery...

James M. Hill 1,2,3,4 and Walter J. Lukiw* 1 Louisiana State University Neuroscience Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA 2 Departments of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA, USA 3 Microbiology, Louisiana State University Health Sciences Center, New Orleans, LA, USA 4 Pharmacology, Louisiana State Universi...

The FASEB Summer Research Conference on Microbial Pathogenesis: Mechanisms of Infectious Disease was held in Colorado, USA in July 2007. The central theme was the interplay between pathogenic microbes and their mammalian hosts. Here, we review the presented research that highlights this theme, including studies of both short-term and long-term interactions between microbes and their hosts.

Introduction: The presence of pathogenic microbial agents and pathogens in organic fertilizers causes health problems and disease transmission. The aim of this study was to evaluate the efficiency of vermicomposting process in improve the microbial quality of the compost produced. Materials and Methods: This experimental study was conducted as a pilot-scale one, in the laboratory of school of...

Food constitutes one of the most important routes of transmission of infectious diseases. Microbial safety and quality of food is a global health concern owing to the emergence and reemergence of foodborne pathogens worldwide recently. Microbial pathogens are disease causing bacteria, viruses, fungi and protozoans [1,2]. Food-harboring microbial pathogens and microbial toxins can lead to foodbo...

Since the discovery of Helicobacter pylori, the urease activity of this bacterial pathogen has been identified as the key factor in infection and acid acclimation in the human stomach. Ureolytic activity plays a key role in the pathogenesis of several bacteria, and urease has also been described as an emerging pathogenic factor during fungal infection. However, urease produced by the oral bacte...

One of the gaping holes in the public health tool kit is the lack of comprehensive knowledge about the occurrence and toxic effects of the full spectrum of chemicals emitted by industrial facilities. The Commission for Environmental Cooperation (CEC) has taken a small step toward filling this void by assembling selected basic toxics data for North America with the 10 June 2009 release of its 12...

The adherence of four Candida species to human buccal epithelial cells (BECs) following treatment with the most commonly consumed dietary carbohydrates was investigated in vitro. Adhesion of C. albicans , C . tropicalis , C. glabrata and C. parapsilosis was significantly promoted by incubation in minimal medium containing a high concentration (500 mM) of fructose, galactose, glucose, maltose, s...

With growing environmental pressures placed on our marine habitats there is concern that the prevalence and severity of diseases affecting marine organisms will increase. Yet relative to terrestrial systems, we know little about the underlying causes of many of these diseases. Moreover, factors such as saprophytic colonizers and a lack of baseline data on healthy individuals make it difficult t...