Double-walled polyurethane/poly(urea-formaldehyde) microcapsules (PU/UF) are prepared for use in self-healing materials. This modified encapsulation procedure combines two chemistries to form more robust capsule shell walls in a single operation. Robust capsules are formed by this procedure as long as the aromatic polyisocyanate prepolymer is soluble in the core liquid and the core liquid is co...

Host-guest assembly in droplet-based microfluidics opens a new avenue for fabricating supramolecular hydrogel microcapsules with high monodispersity and controlled functionality. In this paper, we demonstrate a single emulsion microdroplet platform to prepare microcapsules with supramolecular hydrogel skins from host molecule cucurbit[8]uril and guest polymer anthracene-functionalized hydroxyet...

A nondestructive way to achieve remote, reversible, light-controlled tunable permeability of ultrathin shell microcapsules is demonstrated in this study. Microcapsules based on poly{[2-(methacryloyloxy)ethyl] trimethylammonium iodide} (PMETAI) star polyelectrolyte and poly(sodium 4-styrenesulfonate) (PSS) were prepared by a layer-by-layer (LbL) technique. We demonstrated stable microcapsules wi...

The present investigation was designed to develop, characterize and evaluate mucoadhesive microcapsules of isoniazid employing various mucoadhesive polymers for prolonged gastric intestinal absorption. Sodium alginate is an anionic polymer which can be easily cross-linked with calcium chloride. This is because the calcium ions are bound to carboxylate residues of both mannuronic acid and glucou...

this study was aimed at evaluating the flow behavior characteristics of yogurt enriched with fish oil (fo) microcapsules prepared by complex coacervation method. fo was microencapsulated in gelatin-acacia gum coacervates. then, the microcapsules were dried, and yogurt was produced from the milk enriched with microcapsules powder. rheological characteristics (as measured using a rotational visco...

Hollow multilayered capsules have shown massive potential for being used in the biomedical and biotechnology fields, in applications such as cellular internalization, intracellular trafficking, drug delivery, or tissue engineering. In particular, hollow microcapsules, developed by resorting to porous calcium carbonate sacrificial templates, natural-origin building blocks and the prominent Layer...

In this paper, microcapsules were produced by complex coacervation using gelatin and acacia as wall materials and olive oil as the core substance. Process parameters, such as the dosage of the crosslinker, concentration of the wall materials, pH Value and the ratio between core and wall materials were analyzed in detail. Moreover, crosslinking degree of wall materials was more important in obta...

PURPOSE To develop and validate a method to prepare clarithromycin (CLM) microcapsules to mask the bitter taste and provide effective treatment, and evaluate the quality of microcapsules in detail, especially the in vitro and in vivo pharmacokinetics behavior. METHODS CLM microcapsules were prepared using ethyl cellulose as matrix material by an emulsion solvent diffusion method. The physicoc...

Introduction: Improved drug delivery mechanisms for the treatment of residual peritoneal cancer cells following cytoreduction surgery are needed. Alginate microcapsules are a potentially useful mechanism for delivery of bioengineered cells, but when injected into the peritoneum, their distribution and properties are not well described. Methods: Aliquots of 300, 600 or 1200 microcapsules were in...

How droplet microfluidics can be used to fabricate solid-shelled microcapsules having precisely controlled release behavior is described. Glass capillary devices enable the production of monodisperse double emulsion drops, which can then be used as templates for microcapsule formation. The exquisite control afforded by microfluidics can be used to tune the compositions and geometrical character...