PURPOSE Microdissection testicular sperm extraction has replaced conventional testis biopsies for men with nonobstructive azoospermia and it has become first line treatment. The current problem is that the decision to retrieve tubules is based only on appearance and there is no guarantee that the tubules removed contain sperm. Multiphoton microscopy enables label-free immediate visualization of...

BACKGROUND The aim of this study was to assess the use of testicular sperm for ICSI in azoospermic men with hypogonadotrophic hypogonadism unresponsive to gonadotrophin therapy. METHODS Fifteen patients with hypogonadotrophic hypogonadism who remained azoospermic after hormonal treatment underwent testicular sperm extraction (TESE) and ICSI. These men were recruited from the Egyptian IVF cent...

Background: Although the pathophysiology of the testicular damage associated with varicocele remains unclear, but varicocelectomy is considered a suitable technique for the treatment of individuals with clinical varicocele. The current study was designed to assessed semen parameters, chromatin packaging, and pregnancy outcome before and after varicocelectomy. Materials and Methods: Semen sample...

Clinical outcomes of ICSI when using only five or fewer testicular spermatozoa after cryopreservation have been unsuccessful and are considered to be inferior those fresh from Micro-TESE. A possible cause these poor results has the lack a successful freezing technique. In cases, repeated Micro-TESE simultaneous oocyte pick up available treatment. We developed an innovative ultra-rapid vitrifica...

PURPOSE The improvement of testicular volume, testosterone levels and sperm concentration was suggested to be significantly associated with the number of internal spermatic veins (ISVs) ligated during varicocelectomy. Herein, we investigated preoperative color Doppler ultrasonography (CDU) findings as potential preoperative predictors of the number of ISVs requiring ligation during microsurgica...

Testicular sperm retrieval techniques associated with intracytoplasmic sperm injection have changed the field of male infertility treatment and given many azoospermic men the chance to become biological fathers. Despite the current use of testicular sperm extraction, reliable clinical and laboratory prognostic factors of sperm recovery are still absent. The objective of this article was to revi...

INTRODUCTION Male infertility caused by azoospermia due to non-reconstructable obstruction or non-obstructive azoospermia can be treated by microsurgical epididymal aspiration (MESA) or testicular sperm extraction (TESE) followed by an intracytoplasmatic spermatozoa injection (ICSI). MATERIAL AND METHODS From 9/93 to 6/01, we carried out 1,025 ICSI procedures with aspirated epididymal or test...

BACKGROUND The aim of this study was to investigate whether there is a need for diagnostic biopsies in men with obstructive azoospermia (OA). METHODS Sixty-three adult men with OA due to vasectomy, bilateral inflammation or bilateral aplasia of the vas deferens were included in the study. We determined testicular volume, sexual hormone levels and testicular histologies of right and left teste...

You have accessJournal of UrologyInfertility: Therapy (MP31)1 Sep 2021MP31-06 MICRODISSECTION TESTICULAR SPERM EXTRACTION IS AN EFFECTIVE CHOICE TO OPTIMIZE FERTILITY OUTCOMES IN SEVERE OLIGOZOOSPERMIC PATIENTS WHO HAD PRIOR ONE OR MORE ASSISTED REPRODUCTIVE TECHNOLOGY FAILURE Cheng-Han Tsai, Wei-Jen Chen, I-Shen Huang, Yi-Hsiu and William J. Huang TsaiCheng-Han Tsai More articles by this autho...