The arterial supply of the feline motor cortex is derived from both the anterior and middle cerebral arteries. The anterior cerebral artery supplies most of cortical area 6 (premotor cortex), the intrafundal cruciate and medial postcruciate cortex, (hindlimb motor cortex), and the midline and medial portions of the sensory areas 3a-7. The middle cerebral artery supplies the lateral prorean cort...

A previously healthy 15-month-old girl became pale and lethargic. CT showed subarachnoid hemorrhage. Cerebral angiography showed a 5-mm aneurysm in the M1 segment of the left middle cerebral artery (Fig. 1 A). The anterior cerebral artery was not visualized on the left carotid artery angiogram. Both anterior cerebral arteries filled from the right carotid injection. An additional vessel origina...

Difficulties in achieving focal temporary cerebral ischemia in experimental animals have delayed study of the prevention and treatment of cerebral infarction. We have succeeded in producing focal cerebral infarction by temporary occlusion of brain arteries. Infarction confined to the anterior portion of the thalamus was obtained by simultaneous occlusion of the 4 cerebral arteries: internal car...

We angiographically studied 80 patients within 6 hours after the onset of ischemic supratentorial infarction. From this group we selected 36 patients with middle cerebral artery occlusion who survived. In these 36 patients, we compared the presence of a collateral blood supply during the early phase with the extent of final parenchymal brain damage obtained by computed tomography 3 months after...

A drenergic Mechanisms in Cerebral Blood Vessels: Effect of Tyramine on the Isolated Middle Cerebral Artery of the Goal • Tyramine induces dose-dependent changes in tension of the isolated middle cerebral artery of the goat. Cocaine, phentolamine and reserpine reduce the sensitivity of the tissue to tyramine by factors of 2.8, 3.7 and 3.7, respectively. The norepinephrine (NE) concentration of ...

Difficulties in achieving focal temporary cerebral ischemia in experimental animals have delayed study of the prevention and treatment of cerebral infarction. We have succeeded in producing focal cerebral infarction by temporary occlusion of brain arteries. Infarction confined to the anterior portion of the thalamus was obtained by simultaneous occlusion of the 4 cerebral arteries: internal car...

Histochemical study revealed that transcutaneous injection of ethanol into the vicinity of the pterygopalatine ganglion greatly decreased the positive staining for NADPH diaphorase activity after 1 week in the ipsilateral ganglion of a dog and abolished the staining of perivascular nerves in the middle and posterior cerebral arteries. Transmural electrical stimulation or nicotine produced a rel...

Sildenafil (Viagra), a selective inhibitor of phosphodiesterase 5 (PDE5), induces headache and migraine. Although previously supposed to be a "vascular" headache, no significant cerebral artery dilatation was found in vivo. Thus, we hypothesised that PDE5 may not be present or that sildenafil is less effective on the cGMP hydrolysis in cerebral arteries, and that sildenafil may not be an effect...

The Circle of Willis (CoW) (Figure 1) is a ring-like arterial structure located at the base of the brain. It is the major arterial anastomoses in the brain and is responsible for the distribution of oxygenated blood throughout the cerebral mass. The Internal Carotid (ICA) and Basilar (BA) arteries bring blood into the CoW and are termed afferent arteries. The Anterior (ACA), Middle (MCA), and P...

M ost reported arterial dissections involve the carotid and vertebral arteries in the neck. Within the intracranial arteries, dissections most often involve the vertebral and basilar arteries. Intracranial carotid and middle cerebral artery dissections occur much more rarely and seem to develop in younger individuals compared with patients who develop posterior-circulation intracranial dissecti...