INTRODUCTION The term cancer of unknown primary site (CUP) syndrome is used to describe malignancies in which a complete diagnostic work-up detects metastases in the absence of an identifiable primary tumor. METHODS Based on a selective literature review, national and international guidelines, and the experience of the "Arbeitskreis CUP-Syndrom der Arbeitsgemeinschaft Internistische Onkologie...

OBJECTIVES To investigate the correlation between exposure of footballers in European clubs to match play in the months before the World Cup 2002 and their injuries and performances during that World Cup. METHODS The team doctors at 11 of the best football clubs in Europe prospectively recorded players' exposure and injuries during the 2001-2002 season (July 2001-May 2002). Sixty five players...

Recently the problem of indexing and locating content in peer-to-peer networks has received much attention. Previous work suggests caching index entries at intermediate nodes that lie on the paths taken by search queries, but until now there has been little focus on how to maintain these intermediate caches. This paper proposes CUP, a new comprehensive architecture for Controlled Update Propaga...