Dolutegravir (DTG) is approved in the United States to treat HIV-1-infected patients weighing ≥30 kg. A dispersible DTG tablet formulation was recently developed for pediatric patients. This study compares the pharmacokinetics (PK) of the dispersible tablet with that of a previously evaluated granule formulation. In this randomized, open-label, crossover study, 15 healthy adults received single...

It is an emerging realistic problem on how to promote a high level of technology in the coal industry, find new upgrading powers and create new competitive advantages, which are also the core problems to efficient transformation pattern of economic growth for coal industry in the ‘‘twelfth five-year’’ period, involving the key to China’s energy supply and energy security. Through field surveys ...

The objective of this study was to investigate the adhesion of isolated spoilage bacteria to packaging materials used in the food industry. Microorganisms were isolated from commercial fruit-flavored mineral water in plastic bottles with flocks as a visual defect. The Gram-negative rods were identified using the molecular method through the amplification of a partial region of the 16S rRNA gene...

Water is the most important substance on Earth. While not a mineral itself, water rules the mineral kingdom since interaction with water is fundamental to all geological processes. And water can even slip into the mineral kingdom by freezing into ice. Water occurs in the hydrologic cycle as soil water, groundwater and surface water. We also find water vapor in the atmosphere and frozen water in...

The contact of a steel electrode with water dispersion medium in an open-air system leads to the development of various polymorphic iron oxides and oxyhydroxides on the steel surface. Whereas the usage of distilled water causes the obtaining of Fe(II)-Fe(III) layered double hydroxides (green rust) as a primary mineral phase, but in the presence of inorganic 3d-metal water salt solutions, mixed ...

—The New Zealand mud snail (NZMS), Potamopyrgus antipodarum (Gray), is an invasive species of aquatic snail that is becoming widespread in inland and coastal waters of the western United States. The New Zealand mud snail can have significant impacts on stream ecosystems, as they may consume a large fraction of available algae production and compete with and displace native invertebrates. Even t...

We aim to present an overview of the possible influence of drinking water in general and mineral water in particular in improving glycemic parameters in persons with or without type 2 diabetes. We performed a literature search that produced 15 randomized controlled trials (RCTs) on this topic with mainly small sample sizes. We also discuss relevant observational and animal studies as well as th...

background : we intend to study the inhibitory effect of sulfur compound in ramsar hot spring mineral on tumor-genesis ability of high natural background radiation. objective : the radioprotective effect of sulfur compounds was previously shown on radiation-induced chromosomal aberration, micronuclei in mouse bone marrow cells and human peripheral lymphocyte. ramsar is known for having the high...

agricultural waste biomass generated from agricultural production and food processing industry are abundant, such as durian  peel, mango peel, corn straw, rice bran, corn shell, potato peel and many more. due to low commercial value, these wastes are disposed in landfill, which if not managed properly may cause environmental problems. currently, environmental laws and regulations pertaining to ...