There is disagreement in the literature as to whether lincomycin is primarily a bacteriostatic or a bactericidal agent against gram-positive cocci and also regarding the levels of activity of this agent against susceptible microorganisms. These questions were examined in a study of the effect of inoculum size on the results of tube dilution susceptibility determinations with lincomycin against ...

The present study evaluated the antimicrobial in vitro effects of the salivary proteins lactoferrin and lysozyme on microorganisms involved in the carious process, obtaining their minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Streptococcus mutans (ATCC 25175) and Lactobacillus casei (ATCC 7469) were submitted to broth macrodilution of lysozyme at 80 mg/mL ...

Staphylococcus aureus and Pseudomonas aeruginosa are part of the human microbiota and are also important bacterial pathogens, for which therapeutic options are lacking nowadays. The combined administration of corticosteroids and antimicrobials is commonly used in the treatment of infectious diseases to control inflammatory processes and to minimize potential toxicity of antimicrobials, avoiding...

The emergence of multidrug-resistant strains of Acinetobacter baumannii (MDRAB) constitutes a serious threat to public health and necessitates the discovery of new types of antimicrobial agents. Alyteserin-1c (GLKEIFKAGLGSLVKGIAAHVAS·NH(2)) is a cationic, α-helical peptide that was first isolated from skin secretions of the midwife toad Alytes obstetricans. Synthetic alyteserin-1c displayed pot...

BACKGROUND The excessive and irregular use of antibiotics could result in the generation and diffusion of drug-resistant bacteria. The aim of this study was to investigate the inhibitory effect of Zingiber corallinum Hance essential oil (ZCHO) on drug-resistant bacteria, especially on drug-resistant Acinetobacter baumannii. MATERIAL/METHODS Susceptibility testing was used to evaluate the effe...

The antidermatophytic activity of interpolar methanolic and low polar petroleum ether soxhlet extracts of Sterculia foetida seed was evaluated by agar well diffusion method, The maximum activity was observed in interpolar methanolic extract against C .albicans followed by E. coli, B. Subtilis, P. aeruginosa, S. aureus, T. rubrum, M.gypseum, T.mentagrophytes and T.tonsurans. When compared to low...

The aim of this study was to determine the antibacterial activity Cathormion umbellatum extracts against seven antibiotic-resistant bacteria. pods, leaves and branches C. were extracted with ethanol methanol. disc diffusion assay used screen broth microdilution colorimetric measure minimum inhibitory concentration (MIC) bactericidal (MBC) values. result indicated that highest inhibition zone (1...

We screened forty crude extracts of twenty commonly used to treat bacterial infections for broad sp more affordable alternative against resistant organisms common pathogenic gram negative and gram positiv diffusion method followed by the tube dilution method extract, Escherichia coli showed sensitivity to zone of inhibition ranging from 7 – 19mm, fifteen Pseudomonas aeruginosa was sensitive to ...

nowadays, uncontrolled and frequent use of antibiotics may cause emergence of microbial resistanceamong pathogenic agents. therefore, the use of new synthetic and natural antimicrobial compounds isinevitable. one source of natural compounds in this respect comes from plants. the purpose of this study was to examine the antibacterial effects of peel extracts from sour and sweet pomegranate. meth...

This study was carried out to investigate the potential use of Artemisia arborescens as a source of antimicrobial agents against pathogens. Essential oils of A. arborescens were collected by hydrodistillation. The antibacterial properties of A. arborescens essential oil was studied on the standard gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa), and Staphylococcus aureus (g...