نتایج جستجو برای: mir 137
تعداد نتایج: 58857 فیلتر نتایج به سال:
Article history: Received 4 October 2016 Accepted 4 October 2016 Available online 5 October 2016 to schizophrenia and does this variant have any effect on its function? Computationalmethods can identify the potential targets for a particular miRNA based on the seed sequence it uses to bind to usually the 3′UTR of the target mRNA (Oulas et al., 2015). To determine which targets are relevant to s...
Deregulated expression of microRNAs has the oncogenic or tumor suppressor function in cancer. Since miRNAs in plasma are highly stable, their quantification could contribute to more precise cancer diagnosis, prognosis and therapy prediction. We have quantified expression of seven oncomiRs, namely miR-17/92 cluster (miR-17, miR-18a, miR-19a and miR-20a), miR-21, miR-27a and miR-155, in plasma of...
Tumor suppressor microRNAs (miRNAs) have been explored as agents to target cancer stem cells. Most strategies use a single miRNA mimic and present many disadvantages, such the amount of reagent required diluted effect on genes. miRNAs work in cooperative fashion regulate distinct biological processes pathways. Therefore, we propose that combinations could provide more efficient ways We previous...
This study compared microRNA (miRNA) expression profiles between rheumatic heart disease (RHD) patients and healthy controls to investigate their differential expression and help elucidate their mechanisms of action. Microarray analysis was used to measure miRNA expression, and a total of 133 miRNAs were shown to be significantly upregulated in RHD patients compared with controls, including miR...
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