نتایج جستجو برای: mir 33a

تعداد نتایج: 45423  

2014
Jun Xiao Huan Zhong Yi Zhou Fan Yu Yun Gao Yongju Luo Zhanyang Tang Zhongbao Guo Enyan Guo Xi Gan Ming Zhang Yaping Zhang

MicroRNAs (miRNAs) are endogenous non-coding small RNAs which play important roles in the regulation of gene expression by cleaving or inhibiting the translation of target gene transcripts. Thereinto, some specific miRNAs show regulatory activities in gonad development via translational control. In order to further understand the role of miRNA-mediated posttranscriptional regulation in Nile til...

Journal: :Haematologica 2012
Weixin Wang Meghan Corrigan-Cummins Justin Hudson Irina Maric Olga Simakova Sattva S Neelapu Larry W Kwak John E Janik Barry Gause Elaine S Jaffe Katherine R Calvo

BACKGROUND MicroRNAs can play an important role in tumorigenesis through post-transcriptional regulation of gene expression, and are not well characterized in follicular lymphoma. DESIGN AND METHODS MicroRNA profiles of enriched follicular lymphoma tumor cells from 16 patients were generated by assaying 851 human microRNAs. Tandem gene expression profiles were obtained for predicting microRNA...

Journal: :Molecular pharmacology 2009
Shu-Chen Lu Jing Xu Narumol Chinookoswong Shuying Liu Shirley Steavenson Colin Gegg David Brankow Richard Lindberg Murielle Véniant Wei Gu

Ghrelin is a 28-amino acid peptide secreted mainly by the stomach. Acyl-ghrelin, which binds to and activates the growth hormone secretagogue receptor type 1a (GHS-R1a), is considered to be the active form for its orexigenic effects. It has been demonstrated that peripheral administration of ghrelin stimulates food intake and adiposity in rodents and humans. Accordingly, different approaches to...

Journal: :Cancer biomarkers : section A of Disease markers 2016
Nazila Nouraee Samaneh Khazaei Mohammad Vasei Seyedeh Fatemeh Razavipour Majid Sadeghizadeh Seyed Javad Mowla

BACKGROUND miRNAs have recently been implicated in tumor's microenvironment remodeling and tumor-stromal cells interactions. We have previously reported a signaling role for miR-21, as a secretory molecule released by cancer associated fibroblasts (CAF) adjacent to esophagus tumor cells. OBJECTIVE To discover other potential signaling miRNAs, we employed a co-culture system of esophageal canc...

2016
Binglei Shen Liying Zhang Chuanjiang Lian Chunyan Lu Yonghong Zhang Qiqi Pan Runjun Yang Zhihui Zhao

Milk fat is a key factor affecting milk quality and is also a major trait targeted in dairy cow breeding. To determine how the synthesis and the metabolism of lipids in bovine milk is regulated at the miRNA level, primary mammary epithelial cells (pMEC) derived from two Chinese Holstein dairy cows that produced extreme differences in milk fat percentage were cultured by the method of tissue nub...

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