نتایج جستجو برای: mird
تعداد نتایج: 217 فیلتر نتایج به سال:
Radioiodine therapy is known as the most effective treatment of differentiated thyroid carcinoma (DTC) to ablate remnant thyroid tissue after surgery. In patients with DTC treated with radioiodine, internal radiation dosimetry of radioiodine is useful for radiation risk assessment. The aim of this study is to describe a method to estimate the absorbed dose to the blood using medical internal ra...
Radionuclide therapy requires patient-specific planning of the absorbed dose to target volumes, in most cases tumours, in order to achieve an expected biological effect, taking into account that the absorbed doses to normal organs and tissues should be kept as low as reasonably achievable. Therefore, the calculation of absorbed doses has to be as accurate as possible. The accuracy depends on th...
UNLABELLED Ex vivo autoradiographs of healthy kidney tissue from patients who received (111)In-DTPA-octreotide (DTPA is diethylenetriaminepentaacetic acid) before nephrectomy showed very heterogeneous radioactivity patterns in the kidneys. The consequences of the reported inhomogeneities have been evaluated for radionuclide therapy with (90)Y- DOTA-Tyr(3)-octreotide (DOTA is 1,4,7,10-tetraazacy...
BACKGROUND PET/CT has recently been shown to be a viable alternative to traditional post-infusion imaging methods providing good quality images of 90Y-laden microspheres after selective internal radiation therapy (SIRT). In the present paper, first we assessed the quantitative accuracy of 90Y-PET using an anthropomorphic phantom provided with lungs, liver, spine, and a cylindrical homemade lesi...
The distribution of radiation doses in cancer patients who receive radiotherapy treatment depends on the distance cancerous organ to source, type including density and atoms organ. Even though exposure is focused that will be irradiated, surrounding healthy organs still have a great chance getting exposure. Healthy can exposed within certain period time are thought opportunity experience metast...
Boron Neutron Capture Therapy (BNCT) is a relatively safer technology for killing cancer cells, one of which the Glioblastoma multiforme. One main components BNCT equipment collimator functions as an exit point epithermal neutron particles that hit cells. In addition to experimental method, research can be carried out by modeling, including using MCNPX software based on Monte Carlo Method. This...
Dosimetry is the process of calculating the effective radioactive dose that is applied to tumors and organs respectively as a patient undergoes a peptide receptor radionuclide therapy. This work presents the novel application software ‘DoSE8’ that was developed from our group and that incorporates all necessary image processing steps (registration and segmentation) and data handling for (partly...
The fundamental physical quantity for relating all biologic effects to radiation exposure is the absorbed dose, the energy imparted per unit mass of tissue. Absorbed dose is expressed in units of joules per kilogram (J/kg) and is given the special name gray (Gy). Exposure to ionizing radiation may cause both deterministic and stochastic biologic effects. To account for the relative effect per u...
Bystander and low-dose-rate effects influence the dose-response relationship in a manner not predicted by current dosimetric methodologies. Radiation-induced bystander effects refer to biologic responses in cells that are not traversed by an ionizing radiation track and, thus, not subject to direct energy deposition; that is, the responses occur in nonirradiated cells. Low-dose-rate hypersensit...
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