In recent years, significant advances have been made in the study of colorectal cancer, (CRC) prognosis and outcome. A better understanding of the molecular basis of this disease, as well as the development of new therapeutic approaches to treat it, has dramatically altered its management. It is essential for physicians to have an effective methodology by which to plan treatment, project progno...

The genus Megagraphydrus Hansen, 1999 is revised. Eleven of the twelve previously described species are recognized as valid, with Megagraphydrus wangi Hebauer, 2000 syn. nov. found to be a junior synonym of M. politus Hansen, 1999. Most significantly, Megagraphydrus itself is found to be a junior synonym of Agraphydrus Régimbart, 1903. The species are assigned to the subgenus Agraphydrus. This ...

Ankle injuries are responsible for more than 5 million emergency department visits each year. The AO and Lauge-Hansen classification systems are widely used in the clinical diagnosis of ankle injuries. This study aimed to analyze the intraobserver reliability and interobserver reproducibility of the AO and Lauge-Hansen classification systems. In addition, the authors explored the differences am...

Maykel González Torres, José Rogelio Rodríguez, Susana Vargas, Miriam Estevez González, Ma. del Pilar Carreón-Castro, Gabriel López Calzada, Witold Brostow, and Nathalie Hnatchuk Center of Applied Physics and Advanced Technology, National Autonomous University of Mexico (CFATA-UNAM), Santiago de Querétaro, Mexico Department of Radiation Chemistry, Institute of Nuclear Science, National Autonomo...

PROVIDENCE – Hope is here for the estimated 5.2 million persons1 in the United States with chronic hepatitis C virus (HCV) infections. Twenty-five years after the identification of the virus through cloning techniques, revolutionary direct-acting antiviral agents (DAAs) offer the promise of a cure for a significant number of those affected. Dr. Karen Tashima, Site Director of HIV Clinical Studi...

Toronto physician Miriam Shuchman has spent the last 4 months tracking the research issues surrounding a controversial clinical trial conducted in Toronto. Much of the information appearing in this article was gathered while she was preparing a segment for the CBC Radio program Quirks and Quarks. Earlier, she had reported on similar issues in the US for the Annals of Internal Medicine.

Marisa Rangel, Miriam Falkenberg Immunopathology Laboratory, Division of Scientific Development, Butantan Institute, 05503-900, Sao Paulo, Brazil Laboratory of Toxinology, Department of Physiological Sciences, University of Brasilia, 70910-900, Brasilia, DF, Brazil Department of Pharmaceutical Sciences, Federal University of Santa Catarina, 88040-970, Florianopolis, SC, Brazil Journal of Coasta...

Maria V. Campanón-Toro1, Omar Sierra1, Esther Moreno1,2,3, Miriam Sobrino-García1, Maria T. Gracia-Bara1,2 and Ignacio Dávila1,2,3 1Allergy Department, University Hospital of Salamanca, 37007 Salamanca Spain, 2 IBSAL (Instituto Biosanitario de Salamanca), University Hospital of Salamanca, Spain, and 3Department of Biomedical and Diagnostic Sciences, Salamanca Medical School, University of Salam...